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タイトル
和文:Practical Enantioselective Synthesis of Axially Chiral Biaryl Diphosphonates and Dicarboxylates by Cationic Rhodium(I)/Segphos-Catalyzed Double [2 + 2 + 2] Cycloaddition. 
英文:Practical Enantioselective Synthesis of Axially Chiral Biaryl Diphosphonates and Dicarboxylates by Cationic Rhodium(I)/Segphos-Catalyzed Double [2 + 2 + 2] Cycloaddition. 
著者
和文: Goushi Nishida, Shuichiro Ogaki, Yukinori Yusa, Tohru Yokozawa, Keiichi Noguchi, Ken. Tanaka.  
英文: Goushi Nishida, Shuichiro Ogaki, Yukinori Yusa, Tohru Yokozawa, Keiichi Noguchi, Ken. Tanaka.  
言語 English 
掲載誌/書名
和文:Organic Letters 
英文:Organic Letters 
巻, 号, ページ Vol. 10    No. 13    pp. 2849-2852
出版年月 2008年 
出版者
和文:American Chemical Society 
英文:American Chemical Society 
会議名称
和文: 
英文: 
開催地
和文: 
英文: 
DOI https://doi.org/10.1021/ol801013v
アブストラクト A cationic rhodium(I)/Segphos complex catalyzes a [2 + 2 + 2] cycloaddn. of internal 1,6-diynes MeC竕。CCH2XCH2C竕。CMe (X = O, NTs, 4-BrC6H4SO2N) with a phosphonate- or ester-substituted 1,3-butadiyne RC竕。CC竕。CR [R = P(O)(OEt)2, CO2Et] leading to C2-sym. axially chiral biaryl diphosphonates or dicarboxylates, resp., e.g. I [R = P(O)(OEt)2, CO2Et], in high yields with outstanding ee's. The use of a phosphonate- or ester-substituted 1,3-butadiyne as a cycloaddn. partner and Segphos as a ligand is crucial for the success of this transformation. [on SciFinder(R)]

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