The effects of the repose angle and the basal friction angle in granular flow simulations are discussed in this study. These important parameters characterize the flow behaviors of granular materials. A database of the repose angle, which includes data on the relation between the repose angle and distinct element method (DEM) input parameters, was prepared based on the simulated results of the repose angle. A series of DEM simulations was then performed to quantify the effects of the repose angle and the basal friction angle in granular flow simulations. The obtained results indicate that the basal friction angle strongly affects the run-out distance, and that contribution are much stronger than the repose angle. Therefore, due consideration should be given to the basal friction angle when predicting the run-out distance in granular flow simulations.