In the current wind-resistant design code, buildings are designed to remain elastic. As they become taller, however, wind force on them tends to increase drastically thereby making them more susceptible to plastic deformation. It is, therefore, vital to evaluate the elasto-plastic response of high-rise buildings to wind forces. As such, this paper proposes an elasto-plastic wind-induced multi-degree-of-freedom response prediction method for a passively controlled high-rise building with hysteretic dampers, and examines the accuracy of the proposed method.