There are only few available studies about wind response of base-isolated high-rise buildings. Conventional design wisdom for wind response is to consider peak responses. However, according to observed wind speed and acceleration of a base-isolated high-rise building, the acceleration peak factor is larger than the expected design value. As such, the authors carry out analysis considering two typhoon records for wind speed and acceleration stability. Results show unstable characteristics of wind speed and acceleration, and in certain time duration, unstable characteristics even for 1 minute.