The intersectoral impacts of the COVID-19 pandemic on humanity raises concerns about its implications for sustainable development. Here, we examine a global quantitative impact of COVID-19 pandemic on Sustainable Development Goals (SDGs) across all 17 goals using 65 proxy indicators across 72 countries collected from April 2020 to February 2021. Our data-driven analysis indicated that adverse impacts of the pandemic have been particularly concerned on gender equality (Goal 5), affordable and clean energy (Goal 7), decent work and economic growth (Goal 8), sustainable cities and communities (Goal 11), and responsible consumption and production (Goal 12) with global scores estimated to be −0.38, −0.21, −0.28, −0.22 and −0.16, respectively. Country income level was a variable that strongly differentiates the responses to the pandemic (e.g., lower incomes had 14 negative goals compared to 11 and 4 negative goals assigned to middle- and high-income countries, respectively). However, Goals 5 and 8 were highly impacted worldwide regardless of income status. Furthermore, countries that had already higher performance in SDGs were less impacted by the pandemic, highlighting the importance of progress on the SDGs in increasing societal resilience to pandemics. The findings provide insights into the reinforcement of recovery policies (e.g., protecting vulnerable groups and transitioning to a green economy) and a basis for a quantitative discussion on the sectors to be prioritized.