"戸田 収,細谷 悟史,遠藤 毅,根岸 瑠美,福島 慶子,伊藤 由馬,十川 久美子,PAXTON Thanai,喜井 勲,朴 明宣,大野 敏,竹内 真粧美,横川 隆志,西川 一八,山下 克子,徳永 万喜洋,細谷 孝充,林 宣宏","神経細胞における生体膜ラフトの動作メカニズムの解明","第35回日本分子生物学会年会",,,,,,2012,Dec. "Chikanori Kuramori,Motoki Azuma,Kanako Kume,Yuki Kaneko,Atsushi Inoue,Yuki Yamaguchi,Yasuaki Kabe,Takamitsu Hosoya,Masahiro Kizaki,Makoto Suematsu,Hiroshi Handa","Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus",,"Biochem. Biophys. Res. Commun.",," 379"," 2"," 519-525",2009,Feb. "T. Hosoya,J. Yomoda,M. Muraki,N. Kataoka,T. Hosoya,M. Suzuki,M. Hagiwara,H. Kimura","Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A",,"Genes Cell",,"Vol. 13","No. 3","pp. 233-244",2008,Mar. "S. Ohno,M. Matsui,T. Yokogawa,M. Nakamura,T. Hosoya,T. Hiramatsu,M. Suzuki,N. Hayashi,K. Nishikawa","Site-selective Post-translational Modification of Proteins Using an Unnatural Amino Acid, 3-Azidotyrosine.",,"J. Biochem.",,"Vol. 141","No. 3","pp. 335-343",2007, "T. Hiramatsu,Y. Guo,T. Hosoya","Azidodifluoromethyl-3H-diazirin-3-yl group as an all-in-one functional group for radioisotope-free photoaffinity labeling.",,"Org. Biomol. Chem.",,"Vol. 5","No. 18","pp. 2916-2919",2007, "細谷孝充","標的タンパク質探索の化学",,"化学工業",,"Vol. 58","No. 5","pp. 345-350",2007, "M. Abe,S. Ohno,T. Yokogawa,T. Nakanishi,F. Arisaka,T. Hosoya,T. Hiramatsu,M. Suzuki,T. Ogasawara,T. Sawasaki,K. Nishikawa,M. Kitamura,H. Hori,Y. Endo","Detection of structural changes in a cofactor binding protein by using a wheat germ cell-free protein synthesis system coupled with unnatural amino acid probing.",,"Proteins",,"Vol. 67","No. 3","pp. 643-652",2007, "細谷孝充","アジド基の特性を利用したnon-RI光親和性標識法の開発",,"有機合成化学協会誌",,"Vol. 65","No. 9","pp. 842-851",2007, "T. Fukuhara,T. Hosoya,S. Shimizu,K. Sumi,T. Oshiro,Y. Yoshinaka,M. Suzuki,N. Yamamoto,L. A. Herzenberg,L. A. Herzenberg,M. Hagiwara","Utilization of host SR protein kinases and RNA splicing machinery during viral replication.",,"Proc. Natl. Acad. Sci. USA",,"Vol. 103","No. 30","pp. 11329-11333",2006, "鈴木正昭,土居久志,細谷孝充","生体可視化用分子プローブの創製と活用",,"オプトロニクス",,"Vol. 25","No. 3","pp. 94-100",2006, "Y. Cui,H. Takamatsu,T. Kakiuchi,H. Ohba,Y. Kataoka,C. Yokoyama,H. Onoe,Yu. Watanabe,T. Hosoya,M. Suzuki,R. Noyori,H. Tsukada,Y. Watanabe","Neuroprotection by a Central Nervous System-Type Prostacyclin Receptor Ligand Demonstrated in Monkeys Subjected to Middle Cerebral Artery Occlusion and Reperfusion: A Positron Emission Tomography Study.",,"Stroke",,"Vol. 37","No. 11","pp. 2830-2836",2006, "T. Hosoya,K. Sumi,H. Doi,M. Wakao,M. Suzuki","Rapid methylation on carbon frameworks useful for the synthesis of 11CH3-incorporated PET tracers: Pd(0)-mediated rapid coupling of methyl iodide with an alkenyltributylstannanes leading to a 1-methylalkene.",,"Org. Biomol. Chem.",,"Vol. 4","No. 3","pp. 410-415",2006, "T. Hosoya,T. Hiramatsu,T. Ikemoto,H. Aoyama,T. Ohmae,M. Endo,M. Suzuki","Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca2+ release from sarcoplasmic reticulum of skeletal muscle.",,"Bioorg. Med. Chem. Lett.",,"Vol. 15","No. 5","pp. 1289-1294",2005, "鈴木正昭,土居久志,細谷孝充","脳化学:PET研究基盤を刷新するプローブ創製と 11C新導入法",,"神経研究の進歩",,"Vol. 49","No. 6","pp. 939-947",2005, "T. Hosoya,M. Wakao,Y. Kondo,H. Doi,M. Suzuki","Rapid methylation of terminal acetylenes by the Stille coupling of methyl iodide with alkynyltributylstannanes: a general protocol potentially useful for the synthesis of short-lived 11CH3-labeled PET tracers with a 1-propynyl group.",,"Org. Biomol. Chem.",,"Vol. 2","No. 1","pp. 24-27",2004, "鈴木正昭,土居久志,加藤孝一,細谷孝充,渡辺由美子,渡辺恭良","脳を探る分子プローブ設計:ヒト脳内IP2受容体の分子イメージング",,"日本神経精神薬理学雑誌",,"Vol. 24","No. 4","pp. 221-229",2004, "M. Suzuki,H. Doi,T. Hosoya,B. Langstrom,Y. Watanabe","Rapid methylation on Carbon Frameworks Leading to the Synthesis of a PET Tracer Capable of Imaging a Novel CNS-type Prostacyclin Receptor in Living Human Brain.",,"Trends Anal. Chem.",,"Vol. 23","No. 8","pp. 595-607",2004, "M. Muraki,B. Ohkawara,T. Hosoya,H. Onogi,J. Koizumi,T. Koizumi,K. Sumi,J. Yomoda,M. V. Murray,H. Kimura,K. Furuichi,H. Shibuya,A. R. Krainer,M. Suzuki,M. Hagiwara","Manipulation of alternative splicing by a newly developed inhibitor of Clks.",,"J. Biol. Chem.",,"Vol. 279","No. 23","pp. 24246-24254",2004, "T. Hosoya,T. Hiramatsu,T. Ikemoto,M. Nakanishi,H. Aoyama,A. Hosoya,T. Iwata,K. Maruyama,M. Endo,M. Suzuki","Novel bifunctional probe for radioisotope-free photoaffinity labeling: compact structure comprised of photospecific ligand ligation and detectable tag anchoring units.",,"Org. Biomol. Chem.",,"Vol. 2","No. 5","pp. 637-641",2004, "鈴木正昭,土居久志,細谷孝充,塚田秀夫","先端の分析法?理工学からナノ・バイオまで?/第10章 生体トモグラフィー/第1節 PET",,,"エヌ・ティ?・エス",,,"pp. 814-829",2004, "鈴木正昭,土居久志,細谷孝充,渡辺恭良","Positron Emission Tomography(PET)法による生体の分子イメージング研究と創薬・医療への応用",,"生物物理",,"Vol. 44","No. 6","pp. 265-270",2004, "鈴木正昭,土居久志,細谷孝充,B. Langstrom,渡辺由美子,渡辺恭良","設計PGプローブによるヒト脳内IP2受容体の分子イメージング",,"細胞工学",,"Vol. 22","No. 2","pp. 167-171",2003, "鈴木正昭,土居久志,細谷孝充,渡辺恭良","生体系の非破壊分析(9):PET法による脳内中枢型プロスタサイクリン受容体の分子イメージング",,"現代化学",,"Vol. 387","No. 6","pp. 46-54",2003, "T. Hosoya,H. Aoyama,T. Ikemoto,Y. Kihara,T. Hiramatsu,M. Endo,M. Suzuki","Dantrolene Analogues Revisited: General Synthesis and Specific Functions Capable of Discriminating Two Kinds of Ca2+ Release from Sarcoplasmic Reticulum of Mouse Skeletal Muscle.",,"Bioorg. Med. Chem.",,"Vol. 11","No. 5","pp. 663-673",2003, "T. Hosoya,H. Aoyama,T. Ikemoto,T. Hiramatsu,Y. Kihara,M. Endo,M. Suzuki","[125I]-N-[(3-Azido-5-iodo)benzyl]dantrolene and [125I]-N-{[3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)]benzyl}dantrolene: Photoaffinity Probes Specific for the Physiological Ca2+ Release from Sarcoplasmic Reticulum of Skeletal Muscle.",,"Bioorg. Med. Chem. Lett.",,"Vol. 12","No. 22","pp. 3263-3265",2002, "T. Hamura,T. Hosoya,H. Yamaguchi,Y. Kuriyama,M. Tanabe,M. Miyamoto,Y. Yasui,T. Matsumoto,K. Suzuki","Facile access to versatile polyaromatic building blocks: selectively protected benzocyclobutenedione derivatives via regioselective [2 + 2] cycloaddition of alpha-alkoxybenzyne and ketene silyl acetal.",,"Helv. Chim. Acta.",,"Vol. 85","No. 11","pp. 3589-3604",2002, "M. Ikenoya,H. Hidaka,T. Hosoya,M. Suzuki,N. Yamamoto,Y. Sasaki","Inhibition of Rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.",,"J. Neurochem.",,"Vol. 81","No. 1","pp. 9-16",2002, "H. Takamatsu,H. Tsukada,Yu. Watanabe,Y.-L. Cui,Y. Kataoka,T. Hosoya,M. Suzuki,Y. Watanabe","Specific ligand for a central type prostacyclin receptor attenuates neuronal damage in a rat model of focal cerebral ischemia.",,"Brain Res.",,"Vol. 925","No. 2","pp. 176-182",2002, "M. Suzuki,T. Hosoya,R. Noyori","Handbook of Organopalladium Chemistry for Organic Synthesis / Palladium-catalyzed rearrangements of oxygen functions.",,,"John Wiley & Sons","Vol. 2",,"pp. 2939-2954",2002, "T. Ikemoto,T. Hosoya,H. Aoyama,Y. Kihara,M. Suzuki","Effects of dantrolene and its derivatives on the Ca2+ release in the sarcoplasmic reticulum of mouse skeletal muscle fibres.",,"Br. J. Pharmacol.",,"Vol. 134","No. 4","pp. 729-736",2001, "S. Futagami,Y. Ohashi,K. Imura,T. Hosoya,K. Omori,T. Matsumoto,K. Suzuki","Total synthesis of ravidomycin: revision of absolute and relative stereochemistry.",,"Tetrahedron Lett.",,"Vol. 41","No. 7","pp. 1063-1067",2000, "T. Hosoya,T. Hamura,Y. Kuriyama,M. Miyamoto,T. Matsumoto,K. Suzuki","Silicon-Directed Regioselective [2+2] Cycloaddition of alpha-Alkoxybenzyne and Ketene Silyl Acetals.",,"Synlett",,,"No. 4","pp. 520-522",2000, "K. Furuta,T. Hosoya,K. Tomokiyo,S. Okuda,A. Kuniyasu,H. Nakayama,T. Ishikawa,M. Suzuki","[35S]S-[5-(4-benzoylphenyl)pentyl]glutathione: A Versatile Radioligand Targeting GS-X Pumps with the Ability of Photoaffinity Labeling.",,"Bioorg. Med. Chem. Lett.",,"Vol. 9","No. 18","pp. 2661-2666",1999, "鈴木正昭,古田享史,細谷孝充","「設計分子による生体機能制御ソフトの構築」を目指して",,"有機合成化学協会誌",,"Vol. 55","No. 5","pp. 365-374",1997, "T. Hosoya,Y. Ohashi,T. Matsumoto,K. Suzuki","On the Stereochemistry of Aryl C-Glycosides: Unusual Behavior of Bis-TBDPS Protected Aryl C-Olivosides.",,"Tetrahedron Lett.",,"Vol. 37","No. 5","pp. 663-666",1996, "T. Hosoya,E. Takashiro,Y. Yamamoto,T. Matsumoto,K. Suzuki","Total Syntheses of BE-12406 A and Its C(8)-Vinyl Analog.",,"Heterocycles",,"Vol. 42","No. 1","pp. 397-414",1996, "細谷孝充","Studies on Regio- and Stereoselective Synthesis of Aryl Glycoside Antibiotics.",,,,,,,1995,Mar. "T. Hosoya,Y. Kuriyama,K. Suzuki","Convenient Synthesis of Phthalides via Regioselective Baeyer-Villiger Oxidation of Benzocyclobutenones.",,"Synlett",,,"No. 6","pp. 635-638",1995, "T. Hosoya,T. Hasegawa,Y. Kuriyama,T. Matsumoto,K. Suzuki","[2 + 2] Cycloaddition of Benzyne and Ketene Silyl Acetal as an Efficient Route to Benzocyclobutenones.",,"Synlett",,,"No. 2","pp. 177-179",1995, "T. Hosoya,T. Hasegawa,Y. Kuriyama,K. Suzuki","Stereospecificity in [2 + 2] Cycloaddition of Benzyne and Ketene Silyl Acetal.",,"Tetrahedron Lett.",,"Vol. 36","No. 19","pp. 3377-3380",1995, "K. Suzuki,T. Matsumoto,T. Hosoya","Total Synthesis of the Gilvocarcins.",,"J. Synth. Org. Chem., Jpn.",,"Vol. 53","No. 11","pp. 1045-1054",1995, "T. Hosoya,E. Takashiro,T. Matsumoto,K. Suzuki","Total Synthesis of the Gilvocarcins.",,"J. Am. Chem. Soc.",,"Vol. 116","No. 3","pp. 1004-1015",1994, "T. Hosoya,E. Takashiro,T. Matsumoto,K. Suzuki","First Total Synthesis of BE-12406 A.",,"Tetrahedron Lett.",,"Vol. 35","No. 26","pp. 4591-4594",1994, "鈴木啓介,松本隆司,細谷孝充","ハイブリッド型抗腫瘍性化合物ギルボカルシン類の全合成",,"化学と工業",,"Vol. 46","No. 7","pp. 1103-1105",1993, "T. Matsumoto,T. Hosoya,K. Suzuki","Total Synthesis and Absolute Stereochemical Assignment of Gilvocarcin M.",,"J. Am. Chem. Soc.",,"Vol. 114","No. 9","pp. 3568-3570",1992, "T. Matsumoto,T. Hosoya,M. Katsuki,K. Suzuki","New Efficient Protocol for Aryne Generation. Selective Synthesis of Differentially Protected 1,4,5-Naphthalenetriols.",,"Tetrahedron Lett.",,"Vol. 32","No. 46","pp. 6735-6736",1991, "T. Matsumoto,T. Hosoya,K. Suzuki","OC-Glycoside Rearrangement of Resorcinol Derivatives. Versatile Intermediates in the Synthesis of Aryl C-Glycosides.",,"Synlett",,,"No. 9","pp. 709-711",1991, "T. Matsumoto,T. Hosoya,K. Suzuki","Improvement in OC-Glycoside Rearrangement Approach to C-Aryl Glycosides: Use of 1-O-Acetyl Sugar as Stable but Efficient Glycosyl Donor.",,"Tetrahedron Lett.",,"Vol. 31","No. 32","pp. 4629-4632",1990,