@book{CTT100920307, author = {北口哲也 and 坪井貴司 and 前川文彦}, title = {みんなの生命科学 第2版}, publisher = {化学同人}, year = 2024, } @book{CTT100920305, author = {北口哲也 and 坪井貴司 and 前川文彦}, title = {マリエル生命科学 原著第4版}, publisher = {化学同人}, year = 2023, } @book{CTT100853162, author = {Marie Mita and Devina Wongso and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi}, title = {Development of a single fluorescent protein-based green glucose indicator by semirational molecular design and molecular evolution.}, publisher = {Springer}, year = 2021, } @article{CTT100926938, author = {Bo Zhu and Yukihiko Yamasaki and Takanobu Yasuda and Cheng Qian and Zhirou Qiu and Mitsue Nagamine and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Customizable OpenGUS immunoassay: A homogeneous detection system using β-glucuronidase switch and label-free antibody}, journal = {Biosensors and Bioelectronics}, year = 2024, } @article{CTT100920202, author = {Gaku Sato and Saki Kinoshita and Takahiro G. Yamada and Satoshi Arai and Tetsuya Kitaguchi and Akira Funahashi and Nobuhide Doi and Kei Fujiwara.}, title = {Metabolic tug-of-war between glycolysis and translation revealed by a biochemical reconstitution.}, journal = {ACS Synth Biol}, year = 2024, } @article{CTT100920199, author = {Saki Tsuno and Kazuki Harada and Mina Horikoshi and Marie Mita and Tetsuya Kitaguchi and Masami Yokota Hirai and Mitsuharu Matsumoto and Takashi Tsuboi}, title = {Real-time visualization of cytosolic and mitochondrial ATP dynamics in response to metabolic stress in cultured cells.}, journal = {FEBS Open}, year = 2024, } @article{CTT100920201, author = {Mina Horikoshi and Kazuki Harada and Saki Tsuno and Tetsuya Kitaguchi and Masami Yokota Hirai and Mitsuharu Matsumoto and Shin Terada and Takashi Tsuboi}, title = {Distinct lactate metabolism between hepatocytes and myotubes revealed by live cell imaging with genetically encoded indicators}, journal = {Biochem Biophys Res Commun}, year = 2024, } @article{CTT100920198, author = {Junfeng Wang and Eijiro Maeda and Yuki Tsujimura and Takaya Abe and Hiroshi Kiyonari and Tetsuya Kitaguchi and Hideo Yokota and Takeo Matsumoto}, title = {In situ FRET measurement of cellular tension using CLSMs: Reporter mice expressing an actinin tension sensor}, journal = {Sci Rep}, year = 2023, } @article{CTT100908475, author = {Kana Sasamoto and Takanobu Yasuda and Bo Zhu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Efficient and rapid linker optimization with heterodimeric coiled coils improves the response of fluorescent biosensors comprising antibody and protein M}, journal = {The Analyst}, year = 2023, } @article{CTT100903968, author = {Bo Zhu and Zhe Du and Yancen Dai and Tetsuya Kitaguchi and Sebastian Behrens and Burckhard Seelig}, title = {Nanodroplet-Based Reagent Delivery into Water-in-Fluorinated-Oil Droplets}, journal = {Biosensors}, year = 2023, } @article{CTT100920197, author = {Sohei Hiasa and Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi}, title = {Development of green fluorescent protein-based cAMP indicators for covering a wide range of cAMP concentrations.}, journal = {RSC Advances}, year = 2023, } @article{CTT100908476, author = {Yoshihiro Ito and Ryuichi Sasaki and Sayaka Asari and Takanobu Yasuda and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Efficient Microfluidic Screening Method Using a Fluorescent Immunosensor for Recombinant Protein Secretions}, journal = {Small}, year = 2023, } @article{CTT100899547, author = {Kazuki Harada and Maoko Takashima and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {F-actin determines the time-dependent shift in docking dynamics of glucagon-like peptide-1 granules upon stimulation of secretion}, journal = {FEBS lett}, year = 2023, } @article{CTT100899546, author = {Donnell White III and Lothar Lauterboeck and Parnia Mobasheran and Tetsuya Kitaguchi and Antoine H. Chaanine and Qinglin Yang.}, title = {Real-time visualization of cytosolic and mitochondrial ATP dynamics in response to metabolic stress in cultured cells.}, journal = {Cells}, year = 2023, } @article{CTT100882627, author = {Jiulong Su and Bo Zhu and Akihito Inoue and Hiroyuki Oyama and Izumi Morita and Jinhua Dong and Takanobu Yasuda and Yoshiko Sugita-Konishi and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake and Hiroshi Ueda}, title = {The Patrol Yeast: a new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning}, journal = {Biosensors and Bioelectronics}, year = 2023, } @article{CTT100877603, author = {Bo Zhu and Cheng Qian and Haoxuan Tang and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces}, journal = {Biochemistry}, year = 2023, } @article{CTT100882626, author = {B. Zhu and N. Nosaka and S. Kanamaru and J. Dong and Y. Dai and A. Inoue and Y. Yang and K. Kobayashi and T. Kitaguchi and H. Iwasaki and R. Koike and K. Wakabayashi and H. Ueda}, title = {Rapid and sensitive SARS-CoV-2 detection using a homogeneous fluorescent immunosensor Quenchbody with crowding agents}, journal = {Analyst}, year = 2022, } @article{CTT100899545, author = {Mai Takizawa and Yuri Osuga and Rika Ishida and Marie Mita and Kazuki Harada and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging.}, journal = {Commun Biol}, year = 2022, } @article{CTT100882633, author = {Fumiya Uefune and Toru Aonishi and Tetsuya Kitaguchi and Harumi Takahashi and Susumu Seino and Daisuke Sakano and Shoen Kume}, title = {Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer}, journal = {Diabetes}, year = 2022, } @article{CTT100880996, author = {Yancen Dai and Yuko Sato and Bo Zhu and Tetsuya Kitaguchi and Hiroshi Kimura and Farid J. Ghadess and Hiroshi Ueda}, title = {Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting}, journal = {Chemical Science}, year = 2022, } @article{CTT100899544, author = {Ferdinandus and Madoka Suzuki and Yoshie Harada and Cong Quang Vu and Satya Ranjan Sarker and Shin’ichi Ishiwata and Tetsuya Kitaguchi and Satoshi Arai.}, title = {Modulation of Local Cellular Activities using a Photothermal Dye-Based Subcellular-Sized Heat Spot}, journal = {ACS Nano}, year = 2022, } @article{CTT100875114, author = {Marie Mita and Izumi Sugawara and Kazuki Harada and Motoki Ito and Mai Takizawa and Kentaro Ishida and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics}, journal = {Cell Chem Biol}, year = 2022, } @article{CTT100863138, author = {Akihito Inoue and Takanobu Yasuda and Bo Zhu and Tetsuya Kitaguchi and Akikazu Murakami and Hiroshi Ueda}, title = {Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface}, journal = {Scientific Reports}, year = 2021, } @article{CTT100875112, author = {Keijun Kakihara and Kengo Asamizu and Kei Moritsugu and Masahide Kubo and Tetsuya Kitaguchi and Akinori Endo and Akinori Kidera and Mitsunori Ikeguchi and Akira Kato and Masayuki Komada and Toshiaki Fukushima.}, title = {Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.}, journal = {Commun Biol}, year = 2021, } @article{CTT100858554, author = {Xuerao Ning and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of Fluorescent Immunosensor Quenchbody to Detect His-Tagged Recombinant Proteins Produced in Bioprocess}, journal = {Sensors}, year = 2021, } @article{CTT100858035, author = {T. Yasuda and A. Inoue and T. Kitaguchi and H. Ueda}, title = {Rapid construction of fluorescence quenching-based immunosensor Q-bodies using α-helical coiled-coil peptides}, journal = {Chemical Communications}, year = 2021, } @article{CTT100847093, author = {Yuki Ohmuro-Matsuyama and Tetsuya Kitaguchi and Hiroshi Kimura and Hiroshi Ueda}, title = {Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies}, journal = {ACS Omega}, year = 2021, } @article{CTT100837189, author = {Kazuki Harada and Takami Chihara and Yuki Hayasaka and Marie Mita and Mai Takizawa and Kentaro Ishida and Mary Arai and Saki Tsuno and Mitsuharu Matsumoto and Takeshi Ishihara and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.}, journal = {Sci Rep}, year = 2020, } @article{CTT100836504, author = {Akihito Inoue and Yuki Ohmuro-Matsuyama and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Creation of a Nanobody-Based Fluorescent Immunosensor Mini Q‐body for Rapid Signal-On Detection of Small Hapten Methotrexate}, journal = {ACS Sensors}, year = 2020, } @article{CTT100827505, author = {J. Dong and C. Miyake and T. Yasuda and H. Oyama and I. Morita and T. Tsukahara and M. Takahashi and H.-J. Jeong and T. Kitaguchi and N. Kobayashi and H. Ueda}, title = {PM Q-probe: A fluorescent binding protein that converts many antibodies to a fluorescent biosensor}, journal = {Biosensors and Bioelectronics}, year = 2020, } @article{CTT100821932, author = {Chungyong Han and Beom K. Choi and Seon-Hee Kim and Su-Jung Sim and Seongeun Han and Bomi Park and Yohei Tsuchiya and Masaki Takahashi and Young H. Kim and Hyeon-Seok Eom and Tetsuya Kitaguchi and Hiroshi Ueda and Byoung S. Kwon}, title = {Polymorphic region-specific antibody for evaluation of affinity-associated profile of chimeric antigen receptor}, journal = {Molecular Therapy: Oncolytics}, year = 2020, } @article{CTT100837185, author = {Takumi Nakamura and Kazuki Harada and Taichi Kamiya and Mai Takizawa and Jim Küppers and Kazuo Nakajima and Michael Gütschow and Tetsuya Kitaguchi and Kunihiro Ohta and Tadafumi Kato and Takashi Tsuboi.}, title = {Glutamine-induced signaling pathways via amino acid receptors in enteroendocrine L cell lines.}, journal = {J Mol Endocrinol}, year = 2020, } @article{CTT100837188, author = {Yuki Oe and Xiaowen Wang and Tommaso Patriarchi and Ayumu Konno and Katsuya Ozawa and Kazuko Yahagi and Hirokazu Hirai and Takashi Tsuboi and Tetsuya Kitaguchi and Lin Tian and Thomas J McHugh and Hajime Hirase.}, title = {Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance.}, journal = {Nat Commun}, year = 2020, } @article{CTT100814312, author = {Kanai, Y. and Ohmuro-Matsuyama, Y. and Tanioku, M. and Ushiba, S. and Ono, T. and Inoue, K. and Kitaguchi, T. and Kimura, M. and Ueda, H. and Matsumoto, K.}, title = {Graphene Field Effect Transistor-Based Immunosensor for Ultrasensitive Noncompetitive Detection of Small Antigens}, journal = {ACS Sensors}, year = 2020, } @article{CTT100814313, author = {Jiulong Su and Tetsuya Kitaguchi and Yuki Ohmuro-Matsuyama and Theresa Seah and Farid J. Ghadessy and Shawn Hoon and Hiroshi Ueda}, title = {Transmembrane signaling on a protocell: Creation of receptor-enzyme chimeras for immunodetection of specific antibodies and antigens}, journal = {Scientific Reports}, year = 2019, } @article{CTT100837184, author = {Chihiro Adachi and Naoto Kakinuma and Soohyun Jo and Takayuki Ishii and Yusuke Arai and Satoshi Arai and Tetsuya Kitaguchi and Sen Takeda and Takafumi Inoue.}, title = {Sonic hedgehog enhances calcium oscillations in hippocampal astrocytes.}, journal = {J Biol Chem}, year = 2019, } @article{CTT100837182, author = {Junfeng Wang and Shukei Sugita and Tatsuo Michiue and Takashi Tsuboi and Tetsuya Kitaguchi and Takeo Matsumoto.}, title = {A novel FRET analysis method for a single actin stress fiber: Application to MC3T3-E1 cells during movement on a substrate.}, journal = {J Biorheol}, year = 2019, } @article{CTT100799987, author = {Jiulong Su and Cyrus Beh and Yuki Ohmuro-Matsuyama and Tetsuya Kitaguchi and Shawn Hoon and Hiroshi Ueda}, title = {Creation of stable and strictly regulated enzyme switch for signal-on immunodetection of various small antigens}, journal = {Journal of Bioscience and Bioengineering}, year = 2019, } @article{CTT100793801, author = {M. Mita and M. Ito and I. Sugawara and H. Ueda and T. Tsuboi and T. Kitaguchi}, title = {Green fluorescent protein-based glucose indicators report glucose dynamics in living cells}, journal = {Analytical Chemistry}, year = 2019, } @article{CTT100774089, author = {Satoshi Arai and Rókus Kriszt and Kazuki Harada and Liang-Sheng Looi and Shogo Matsuda and Devina Wongso and Satoshi Suo and Shoichi Ishiura and Yu-Hua Tseng and Michael Raghunath and Toshiro Ito and Takashi Tsuboi and Tetsuya Kitaguchi.}, title = {RGB-color intensiometric indicators visualize spatiotemporal dynamics of ATP in single cells.}, journal = {}, year = 2018, } @article{CTT100761172, author = {Jiulong Su and Jinhua Dong and Tetsuya Kitaguchi and Yuki Omuro and Hiroshi Ueda}, title = {Noncompetitive homogeneous immunodetection of small molecules based on beta-glucuronidase complementation}, journal = {Analyst}, year = 2018, } @article{CTT100775208, author = {Harada, Kazuki and Ito, Motoki and Wang, Xiaowen and Tanaka, Mika and Wongso, Devina and Konno, Ayumu and Hirai, Hirokazu and Hirase, Hajime and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging}, journal = {Scientific Reports}, year = 2017, } @article{CTT100775206, author = {Harada, Kazuki and Tetsuya Kitaguchi and Kamiya, Taichi and Aung, Kyaw Htet and Nakamura, Kazuaki and Ohta, Kunihiro and Tsuboi, Takashi}, title = {Lysophosphatidylinositol-induced activation of the cation channel TRPV2 triggers glucagon-like peptide-1 secretion in enteroendocrine L cells}, journal = {Journal of Biological Chemistry}, year = 2017, } @article{CTT100775204, author = {Hou, Yanyan and Tetsuya Kitaguchi and Kriszt, Rokus and Tseng, Yu-Hua and Raghunath, Michael and Suzuki, Madoka}, title = {Ca2+- associated triphasic pH changes in mitochondria during brown adipocyte activation}, journal = {Molecular Metabolism}, year = 2017, } @article{CTT100745299, author = {Devina Wongso and Jinhua Dong and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Flashbody: a next generation Fluobody with fluorescence intensity enhanced by antigen binding}, journal = {Analytical Chemistry}, year = 2017, } @article{CTT100775207, author = {Kriszt, Rokus and Arai, Satoshi and Itoh, Hideki and Lee, Michelle H. and Goralczyk, Anna G. and Ang, Xiu Min and Cypess, Aaron M. and White, Andrew P. and Shamsi, Farnaz and Xue, Ruidan and Lee, Jung Yeol and Lee, Sung-Chan and Hou, Yanyan and Tetsuya Kitaguchi and Sudhaharan, Thankiah and Ishiwata, Shin'ichi and Lane, E. Birgitte and Chang, Young-Tae and Tseng, Yu-Hua and Suzuki, Madoka and Raghunath, Michael}, title = {Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes}, journal = {Scientific Reports}, year = 2017, } @article{CTT100775205, author = {Matsuda, Shogo and Harada, Kazuki and Ito, Motoki and Takizawa, Mai and Wongso, Devina and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {Generation of a cGMP Indicator with an Expanded Dynamic Range by Optimization of Amino Acid Linkers between a Fluorescent Protein and PDE5 alpha}, journal = {Acs Sensors}, year = 2017, } @article{CTT100775209, author = {Hou, Yanyan and Arai, Satoshi and Tetsuya Kitaguchi and Suzuki, Madoka}, title = {Intracellular bottom-up generation of targeted nanosensors for single-molecule imaging}, journal = {Nanoscale}, year = 2016, } @article{CTT100775301, author = {Junfeng Wang and Masahiro Ito and Wenhao Zhong and Shukei Sugita and Tatsuo Michiue and Takashi Tsuboi and Tetsuya Kitaguchi and Takeo Matsumoto.}, title = {Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor.}, journal = {J Biomech Sci Eng}, year = 2016, } @article{CTT100775211, author = {Yamashita, Satoshi and Tsuboi, Takashi and Ishinabe, Nanako and Tetsuya Kitaguchi and Michiue, Tatsuo}, title = {Wide and high resolution tension measurement using FRET in embryo}, journal = {Scientific Reports}, year = 2016, } @article{CTT100775210, author = {Medina, Johan and Nakagawa, Yuko and Nagasawa, Masahiro and Fernandez, Anny and Sakaguchi, Kazushige and Tetsuya Kitaguchi and Kojima, Itaru}, title = {Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose}, journal = {Journal of Biological Chemistry}, year = 2016, } @article{CTT100775213, author = {Oya, Manami and Tetsuya Kitaguchi and Harada, Kazuki and Numano, Rika and Sato, Takahiro and Kojima, Masayasu and Tsuboi, Takashi}, title = {Low glucose-induced ghrelin secretion is mediated by an ATP-sensitive potassium channel}, journal = {Journal of Endocrinology}, year = 2015, } @article{CTT100775212, author = {Harada, Kazuki and Tetsuya Kitaguchi and Tsuboi, Takashi}, title = {Integrative function of adrenaline receptors for glucagon-like peptide-1 exocytosis in enteroendocrine L cell line GLUTag}, journal = {Biochemical and Biophysical Research Communications}, year = 2015, } @article{CTT100775214, author = {Odaka, Haruki and Arai, Satoshi and Inoue, Takafumi and Tetsuya Kitaguchi}, title = {Genetically-Encoded Yellow Fluorescent cAMP Indicator with an Expanded Dynamic Range for Dual-Color Imaging}, journal = {Plos One}, year = 2014, } @article{CTT100775218, author = {Shimozono, Satoshi and Iimura, Tadahiro and Kitaguchi, Tetsuya and Higashijima, Shin-ichi and Miyawaki, Atsushi and Tetsuya Kitaguchi}, title = {Visualization of an endogenous retinoic acid gradient across embryonic development}, journal = {Nature}, year = 2013, } @article{CTT100775215, author = {Tetsuya Kitaguchi and Oya, Manami and Wada, Yoshiko and Tsuboi, Takashi and Miyawaki, Atsushi}, title = {Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells}, journal = {Biochemical Journal}, year = 2013, } @article{CTT100775216, author = {Oya, Manami and Tetsuya Kitaguchi and Pais, Ramona and Reimann, Frank and Gribble, Fiona and Tsuboi, Takashi}, title = {The G Protein-coupled Receptor Family C Group 6 Subtype A (GPRC6A) Receptor Is Involved in Amino Acid-induced Glucagon-like Peptide-1 Secretion from GLUTag Cells}, journal = {Journal of Biological Chemistry}, year = 2013, } @article{CTT100775217, author = {Oya, Manami and Tetsuya Kitaguchi and Yanagihara, Yu and Numano, Rika and Kakeyama, Masaki and Ikematsu, Kazuya and Tsuboi, Takashi}, title = {Vesicular nucleotide transporter is involved in ATP storage of secretory lysosomes in astrocytes}, journal = {Biochemical and Biophysical Research Communications}, year = 2013, } @article{CTT100775219, author = {Sato, Mai and Kitaguchi, Tetsuya and Numano, Rika and Ikematsu, Kazuya and Kakeyama, Masaki and Murata, Masayuki and Sato, Ken and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {The small GTPase Cdc42 modulates the number of exocytosis-competent dense-core vesicles in PC12 cells}, journal = {Biochemical and Biophysical Research Communications}, year = 2012, } @article{CTT100775220, author = {Mori, Ryoichi and Ikematsu, Kazuya and Kitaguchi, Tetsuya and Kim, Sang E. and Okamoto, Momoko and Chiba, Takuya and Miyawaki, Atsushi and Shimokawa, Isao and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {Release of TNF-alpha from macrophages is mediated by small GTPase Rab37}, journal = {European Journal of Immunology}, year = 2011, } @article{CTT100775221, author = {Tsuboi, Takashi and Kitaguchi, Tetsuya and Karasawa, Satoshi and Fukuda, Mitsunori and Miyawaki, Atsushi and Tetsuya Kitaguchi}, title = {Age-dependent Preferential Dense-Core Vesicle Exocytosis in Neuroendocrine Cells Revealed by Newly Developed Monomeric Fluorescent Timer Protein}, journal = {Molecular Biology of the Cell}, year = 2010, } @article{CTT100775224, author = {Aoki, Ryo and Kitaguchi, Tetsuya and Miyawaki, Atsushi and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {Myosin II modulates fusion pore opening period via cortical F-actin reorganization}, journal = {Journal of Physiological Sciences}, year = 2010, } @article{CTT100775223, author = {Aoki, Ryo and Kitaguchi, Tetsuya and Oya, Manami and Yanagihara, Yu and Sato, Mai and Miyawaki, Atsushi and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis}, journal = {Biochemical Journal}, year = 2010, } @article{CTT100775222, author = {Tsuboi, Takashi and Kitaguchi, Tetsuya and Karasawa, Satoshi and Fukuda, Mitsunori and Miyawaki, Atsushi and Tetsuya Kitaguchi}, title = {Age-dependent preferential secretory vesicle exocytosis in neuroendocrine cells}, journal = {Journal of Physiological Sciences}, year = 2010, } @article{CTT100775226, author = {Aoki, Ryo and Kitaguchi, Tetsuya and Tsuboi, Takashi and Tetsuya Kitaguchi}, title = {MYOSIN II REGULATES "KISS-AND-RUN" DENSE-CORE EXOCYTOSIS REVEALED BY TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY}, journal = {Journal of Physiological Sciences}, year = 2009, } @article{CTT100775225, author = {Sugiyama, Mayu and Sakaue-Sawano, Asako and Iimura, Tadahiro and Fukami, Kiyoko and Kitaguchi, Tetsuya and Kawakami, Koichi and Okamoto, Hitoshi and Higashijima, Shin-ichi and Miyawaki, Atsushi and Tetsuya Kitaguchi}, title = {Illuminating cell-cycle progression in the developing zebrafish embryo}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = 2009, } @article{CTT100775227, author = {Kitaguchi, Tetsuya and Kawakami, Koichi and Kawahara, Atsuo and Tetsuya Kitaguchi}, title = {Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesis}, journal = {Mechanisms of Development}, year = 2009, } @article{CTT100775229, author = {Futatsugi, A and Nakamura, T and Yamada, MK and Ebisui, E and Nakamura, K and Uchida, K and Kitaguchi, T and Takahashi-Iwanaga, H and Noda, T and Aruga, J and Mikoshiba, K and Tetsuya Kitaguchi}, title = {IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism}, journal = {Science}, year = 2005, } @article{CTT100775228, author = {Kitaguchi, T and Swartz, KJ and Tetsuya Kitaguchi}, title = {An inhibitor of TRPV1 channels isolated from funnel web spider venom}, journal = {Biochemistry}, year = 2005, } @article{CTT100775231, author = {Kitaguchi, T and Sukhareva, M and Swartz, KJ and Tetsuya Kitaguchi}, title = {Stabilizing the closed gate of the Shaker Kv channel with a hydrophobic seal}, journal = {Biophysical Journal}, year = 2004, } @article{CTT100775230, author = {Kitaguchi, T and Sukhareva, M and Swartz, KJ and Tetsuya Kitaguchi}, title = {Stabilizing the closed S6 gate in the Shaker K-v channel through modification of a hydrophobic seal}, journal = {Journal of General Physiology}, year = 2004, } @article{CTT100775233, author = {Kitaguchi, T and Sukhareva, M and Swartz, KJ and Tetsuya Kitaguchi}, title = {The non-conducting mechanism of the V478W mutation in Shaker Kv channels}, journal = {Biophysical Journal}, year = 2003, } @article{CTT100775232, author = {Sukhareva, M and Kitaguchi, T and Swartz, K and Tetsuya Kitaguchi}, title = {A mutation within the activation gate of the Shaker K+ channel decreasing single channel conductance}, journal = {Biophysical Journal}, year = 2003, } @article{CTT100775234, author = {Kitaguchi, T and Mizugishi, K and Hatayama, M and Aruga, J and Mikoshiba, K and Tetsuya Kitaguchi}, title = {Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry}, journal = {Development Growth & Differentiation}, year = 2002, } @article{CTT100775236, author = {Kitaguchi, Tetsuya and Nagai, Takeharu and Nakata, Katsunori and Aruga, Jun and Mikoshiba, Katsuhiko and Tetsuya Kitaguchi}, title = {Zic3 is involved in the left-right specification of the Xenopus embryo}, journal = {Development Growth and Differentiation}, year = 2001, } @article{CTT100775235, author = {Kitaguchi, T and Nakata, K and Nagai, T and Aruga, J and Mikoshiba, K and Tetsuya Kitaguchi}, title = {Xenopus Polycomblike 2 (XPcl2) controls anterior to posterior patterning of the neural tissue}, journal = {Development Genes and Evolution}, year = 2001, } @article{CTT100775237, author = {Kitaguchi, T and Nagai, T and Nakata, K and Aruga, J and Mikoshiba, K and Tetsuya Kitaguchi}, title = {Zic3 is involved in the left-right specification of the Xenopus embryo}, journal = {Development}, year = 2000, } @article{CTT100775239, author = {Nakata, Katsunori and Nagai, Takeharu and Koyabu, Yoshio and Kitaguchi, Tetsuya and Aruga, Jun and Mikoshiba, Katsuhiko and Tetsuya Kitaguchi}, title = {Xenopus Zic family and its role in neural and neural crest development}, journal = {Society for Neuroscience Abstracts}, year = 1999, } @article{CTT100775238, author = {Kitaguchi, T and Murata, M and Iijima, K and Kamide, K and Imagawa, T and Ikeda, Y and Tetsuya Kitaguchi}, title = {Characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib alpha: A potential substitute for platelet transfusion}, journal = {Biochemical and Biophysical Research Communications}, year = 1999, } @article{CTT100775241, author = {Kitaguchi, T and Murata, M and Ambo, H and Ikeda, Y and Tetsuya Kitaguchi}, title = {Characterization of cDNA encoding full-length mouse platelet glycoprotein IX}, journal = {Blood Coagulation & Fibrinolysis}, year = 1998, } @article{CTT100775242, author = {Aruga, Jun and Nagai, Takeharu and Nakata, Katsunori and Kitaguchi, Tetsuya and Mizugishi, Kiyomi and Mikoshiba, Katsuhiko and Tetsuya Kitaguchi}, title = {Roles of Zic family in neural development}, journal = {Neuroscience Research Supplement}, year = 1998, } @article{CTT100775244, author = {Kitaguchi, T and Watanabe, N and Ambo, H and Moriki, A and Handa, M and Yagi, K and Zama, T and Isshiki, I and Watanabe, R and Murata, M and Ikeda, Y and Tetsuya Kitaguchi}, title = {Characterization of the gene encoding mouse platelet glycoprotein Ib beta.}, journal = {Blood}, year = 1997, } @article{CTT100775246, author = {Moriki, T and Murata, M and Kitaguchi, T and Anbo, H and Handa, M and Watanabe, K and Takahashi, H and Ikeda, Y and Tetsuya Kitaguchi}, title = {Expression and functional characterization of an abnormal platelet membrane glycoprotein Ib alpha (Met(239)->Val) reported in patients with platelet-type von Willebrand disease}, journal = {Blood}, year = 1997, } @article{CTT100775243, author = {Kitaguchi, T and Murata, M and Anbo, H and Moriki, T and Ikeda, Y and Tetsuya Kitaguchi}, title = {Characterization of the gene encoding mouse platelet glycoprotein Ib beta}, journal = {Thrombosis Research}, year = 1997, } @article{CTT100775248, author = {Kitaguchi, T and Murata, R and Lijima, K and Okada, M and Amatsuji, Y and Kamide, K and Imagawa, T and Matsuda, H and Ruggeri, ZM and Ikeda, Y and Tetsuya Kitaguchi}, title = {Liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib alpha enhance ristocetin-induced platelet aggregation}, journal = {Thrombosis and Haemostasis}, year = 1997, } @article{CTT100775249, author = {Kitaguchi, T and Murata, M and Ikeda, Y and Tetsuya Kitaguchi}, title = {[Establishment and characterization of transgenic mice expressing human platelet glycoprotein Ib alpha].}, journal = {Rinsho byori. The Japanese journal of clinical pathology}, year = 1997, } @article{CTT100775250, author = {Okada, M and Murata, M and Suzuki, H and Kitaguchi, T and Handa, M and Watanabe, K and Sakai, K and Tanoue, K and Ikeda, Y and Tetsuya Kitaguchi}, title = {von Willebrand factor binding to glycoprotein Ib/IX induces platelet shape change under high shear stress conditions - An electron microscopic study}, journal = {Thrombosis and Haemostasis}, year = 1997, } @article{CTT100775247, author = {Iijima, K and Murata, M and Nakamura, K and Kitaguchi, T and Handa, M and Watanabe, K and Fujimura, Y and Yoshioka, A and Ikeda, Y and Tetsuya Kitaguchi}, title = {High shear stress attenuates agonist-induced, glycoprotein IIb/IIIa-mediated platelet aggregation when von Willebrand factor binding to glycoprotein Ib/IX is blocked}, journal = {Biochemical and Biophysical Research Communications}, year = 1997, } @article{CTT100775245, author = {Kitaguchi, Tetsuya and Watanabe, Naohide and Ambo, Hironobu and Moriki, Takanori and Handa, Makoto and Yagi, Kanako and Zama, Takeru and Isshiki, Ikuko and Watanabe, Reiko and Murata, Mitsuru and Ikeda, Yasuo and Tetsuya Kitaguchi}, title = {Characterization of the gene encoding mouse platelet glycoprotein Ibbeta}, journal = {Blood}, year = 1997, } @article{CTT100775251, author = {Kitaguchi, Tetsuya and Murata, Mitsuru and Iijima, Kaori and Okada, Mitsuhiro and Amatsuji, Yasuo and Kamiide, Kaeko and Imagawa, Takashi and Matsuda, Hiroshi and Ruggeri, Zaverio and Ikeda, Yasuo and Tetsuya Kitaguchi}, title = {Construction and functional characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib-alpha}, journal = {Blood}, year = 1996, } @article{CTT100775252, author = {Kitaguchi, T and Murata, M and Iijima, K and Okada, M and Amatsuji, Y and Kamiide, K and Imagawa, T and Matsuda, H and Ruggeri, Z and Ikeda, Y and Tetsuya Kitaguchi}, title = {Construction and functional characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein lb alpha.}, journal = {Blood}, year = 1996, } @article{CTT100775256, author = {Moriki, T and Murata, M and Kitaguchi, T and Watanabe, R and Yokoyama, K and Handa, M and Watanabe, K and Ikeda, Y and Tetsuya Kitaguchi}, title = {In vitro evaluation of antiplatelet efficacy of a recombinant, soluble platelet membrane receptor derived from a variant glycoprotein Ib alpha.}, journal = {Blood}, year = 1996, } @article{CTT100775257, author = {Moriki, Tokanori and Murata, Mitsuru and Kitaguchi, Tetsuya and Watanabe, Reiko and Yokoyama, Kenji and Handa, Makoto and Watanabe, Kiyoaki and Ikeda, Yasuo and Tetsuya Kitaguchi}, title = {In vitro evaluation of antiplatelet efficacy of a recombinant, soluble platelet membrane receptor derived from a variant glycoprotein Ib-alpha}, journal = {Blood}, year = 1996, } @article{CTT100775253, author = {Okada, M and Murata, M and Suzuki, H and Kitaguchi, T and Handa, M and Watanabe, K and Sakai, K and Tanoue, K and Ikeda, Y and Tetsuya Kitaguchi}, title = {Electron microscopic analysis of shear-induced platelet aggregation}, journal = {Blood}, year = 1996, } @article{CTT100775254, author = {Okada, Mitsuhiro and Murata, Mitsuru and Suzuki, Hidenori and Kitaguchi, Tetsuya and Handa, Makoto and Watanabe, Kiyoaki and Sakai, Kiyotaka and Tanoue, Kenjiro and Ikeda, Yasuo and Tetsuya Kitaguchi}, title = {Electron microscopic analysis of shear-induced platelet aggregation}, journal = {Blood}, year = 1996, } @article{CTT100775255, author = {Kitaguchi, T and Murata, M and Kuramochi, T and Kobayashi, K and Ito, M and Ueyama, Y and Nomura, T and Hikichi, K and Miyakawa, Y and Handa, M and Hiraoka, Y and Aiso, S and Ikeda, Y and Tetsuya Kitaguchi}, title = {Establishment and characterization of transgenic mice expressing human platelet glycoprotein Ib alpha}, journal = {Biochemical and Biophysical Research Communications}, year = 1996, } @inproceedings{CTT100920319, author = {北口哲也}, title = {酵母とバイオセンサーの融合が拓く分析技術}, booktitle = {第205回酵母細胞研究会例会 要旨集}, year = 2024, } @inproceedings{CTT100920345, author = {Cheng Qian and Ayumu Ninomiya and Natsuki Shibukawa and Hiroshi Ueda and Takanobu Yasuda and Bo Zhu and Tetsuya Kitaguchi}, title = {PMBiT: A bioluminescent probe for large antigen detection}, booktitle = {The Joint Congress of 21st International Union for Pure and Applied Biophysics}, year = 2024, } @inproceedings{CTT100920347, author = {Yinghui Yang and Akihito Inoue and Takanobu Yasuda and Hiroshi Ueda and Bo Zhu and Tetsuya Kitaguchi}, title = {Fabrication of a nanobody-based ratiometric bioluminescent immunosensor for point-of-care testing}, booktitle = {The Joint Congress of 21st International Union for Pure and Applied Biophysics}, year = 2024, } @inproceedings{CTT100920344, author = {Takanobu Yasuda and Bo Zhu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {A bioluminescent immunosensor based on “Trap & Release” of luciferase-derived peptide fused to antibody}, booktitle = {The Joint Congress of 21st International Union for Pure and Applied Biophysics}, year = 2024, } @inproceedings{CTT100920343, author = {Bo Zhu and Yukihiko Yamasaki and Takanobu Yasuda and Cheng Qian and Zhirou Qiu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {A one-pot detection system using β-glucuronidase-based enzyme switch and label-free antibody}, booktitle = {The Joint Congress of 21st International Union for Pure and Applied Biophysics}, year = 2024, } @inproceedings{CTT100920538, author = {Yuri Osuga and Kazuki Harada and Tomomi Taniguchi and Tetsuya Kitaguchi and Masami Hirai and Mitsuharu Matsumoto and Takashi Tsuboi}, title = {Regulatory mechanism of glucagon-like peptide-1 secretion by taurine in enteroendocrine cells}, booktitle = {第101回日本生理学会大会 要旨集}, year = 2024, } @inproceedings{CTT100920537, author = {Saki Tsuno and Kazuki Harada and Mina Horikoshi and Marie Mita and Tetsuya Kitaguchi and Masami Hirai-Yokota and Mitsuharu Matsumoto and Takashi Tsuboi}, title = {Imaging analysis of metabolic kinetics in hepatocytes during glucosedepletion and reperfusion}, booktitle = {第101回日本生理学会大会 要旨集}, year = 2024, } @inproceedings{CTT100920536, author = {小野義光 and 有坂亮汰 and 二宮歩武 and 柴田貴広 and 内田浩二 and 安田貴信 and 朱博 and 董金華 and 上田宏 and 北口哲也}, title = {ゲノム編集によるオープンサンドイッチ免疫測定用抗体の構築と均一測定系への展開}, booktitle = {化学工学会第89年会 要旨集}, year = 2024, } @inproceedings{CTT100920535, author = {Li Tian and Keisuke Yamashita and Takanobu Yasuda and Takashi Tsuboi and Bo Zhu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Single fluorescent protein-based biosensor for monitoring Intracellular IP3 dynamics}, booktitle = {化学工学会第89年会 要旨集}, year = 2024, } @inproceedings{CTT100911877, author = {Bo Zhu and Yukihiko Yamasaki and Takanobu Yasuda and Cheng Qian and Zhirou Qiu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {A customizable one-pot detection system using β-glucuronidase switch and label-free antibody}, booktitle = {化学工学会第89年会 要旨集}, year = 2024, } @inproceedings{CTT100915126, author = {井上暁人 and 朱博 and 安田貴信 and 水谷圭佑 and 小林健 and 北口哲也}, title = {タンパク質言語モデルを用いた一変異効果予測による蛍光免疫センサーの機能向上}, booktitle = {化学工学会第89年会 要旨集}, year = 2024, } @inproceedings{CTT100915130, author = {安田 貴信 and 朱 博 and 上田 宏 and 北口 哲也}, title = {発光酵素断片のトラップ&リリースに基づく抗原検出法}, booktitle = {化学工学会第89年会 要旨集}, year = 2024, } @inproceedings{CTT100920539, author = {岡崎駿斗 and 北口哲也 and 長山和亮 and 上杉薫}, title = {蛍光共鳴エネルギー移動に基づく細胞力センサ開発に関する研究}, booktitle = {日本機械学会関東支部 関東学生会第63回学生員卒業研究発表講演会 要旨集}, year = 2024, } @inproceedings{CTT100915131, author = {渋川 夏希 and 笹本 佳那 and 瀬尾 秀宗 and 安田 貴信 and 朱 博 and 太田 邦史 and 上田 宏 and 北口 哲也}, title = {バイオセンサーに変換可能な抗体の取得に向けた蛍光プローブタンパク質の開発}, booktitle = {化学工学会第89年会 要旨集}, year = 2024, } @inproceedings{CTT100920318, author = {北口哲也}, title = {分子認識を光や酵素活性で解き明かす}, booktitle = {日本生物工学会 2023年度 第1回非線形バイオシステム研究部会公開セミナー 要旨集}, year = 2024, } @inproceedings{CTT100920534, author = {笹本佳那 and 安田貴信 and 朱博 and 上田宏 and 北口哲也}, title = {順平行コイルドコイルペプチド型蛍光プローブによる蛍光免疫センサの応答向上}, booktitle = {第12回日本生物工学会東日本支部コロキウム 要旨集}, year = 2024, } @inproceedings{CTT100920374, author = {井上暁人 and 安田貴信 and 大内将司 and 北口哲也}, title = {ウサギ抗体を用いたクエンチ型cAMP蛍光免疫センサーの開発}, booktitle = {第2回日本抗体学会学術大会要旨集}, year = 2023, } @inproceedings{CTT100920530, author = {大須賀佑里 and 谷口智海 and 原田一貴 and 北口哲也 and 坪井貴司}, title = {消化管ホルモン分泌に対するL-カルニチンの作用}, booktitle = {第46回日本分子生物学会年会 要旨集}, year = 2023, } @inproceedings{CTT100920375, author = {Zixu Feng and 相原寛史 and 桜庭俊 and Yanyan Hou and 吉田啓亮 and 安田貴信 and Bo Zhu and 上田宏 and 伊藤寿朗 and 北口哲也}, title = {生細胞イメージングに適用可能なジベレリン蛍光免疫センサーへの改良}, booktitle = {第2回日本抗体学会学術大会要旨集}, year = 2023, } @inproceedings{CTT100920531, author = {角沙樹 and 原田一貴 and 堀越美菜 and 三田真理恵 and 北口哲也 and 平井優美 and 松本光晴 and 坪井貴司}, title = {肝細胞における代謝プロセス切替時の細胞内代謝産物の可視化解析}, booktitle = {第46回日本分子生物学会年会 要旨集}, year = 2023, } @inproceedings{CTT100920532, author = {Satoshi Arai and Nguyen Thi Ngoc Loan and Aki Kawamura and Nahoko Shimizu and Yasushi Okada and Tetsuya Kitaguchi and Cong Quang Vu}, title = {A green color fluorescence lifetime-based biosensor for quantitative imaging of intracellular ATP in multicellular system}, booktitle = {第46回日本分子生物学会年会 要旨集}, year = 2023, } @inproceedings{CTT100920533, author = {北口哲也}, title = {蛍光プローブ-開発の流儀-}, booktitle = {金沢大学新学術創成研究機構 異分野融合セミナー}, year = 2023, } @inproceedings{CTT100908478, author = {安田貴信 and 朱博 and 上田宏 and 北口哲也}, title = {生物発光免疫センサーの発光活性増大機構の解明とその原理の 全長抗体への展開}, booktitle = {第2回日本抗体学会学術大会要旨集}, year = 2023, } @inproceedings{CTT100920341, author = {Yuri Osuga and Mai Takizawa and Rika Ishida and Marie Mita and Kazuki Harada and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {Intracellular cGMP dynamics during incretin secretion revealed by red fluorescent protein-based cGMP sensor}, booktitle = {Neuroscience 2023}, year = 2023, } @inproceedings{CTT100920342, author = {Takeo Matsumoto and Junfeng Wang and Eijiro Maeda and Yuki Tsujimura and Hideo Yokota and Tetsuya Kitaguchi}, title = {Transgenic mice expressing FRET-based actinin tension sensor for the measurement of intracellular tension in tissues with conventional clsms.}, booktitle = {The 12th Asian Pacific Conference on Biomechanics}, year = 2023, } @inproceedings{CTT100920340, author = {Kazuki Harada and Maoko Takashima and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {Role of actin in time-dependent shift of docking dynamics of glucagon-like peptide-1 granules during biphasic exocytosis}, booktitle = {The 10th Federation of the Asian and Oceanian Pyshiological Societies Congress}, year = 2023, } @inproceedings{CTT100920315, author = {北口哲也}, title = {トラップ&リリースが繋いだ蛍光免疫センサーの発光への道}, booktitle = {生物発光化学発光研究会 第38回学術講演会 要旨集}, year = 2023, } @inproceedings{CTT100907587, author = {水谷圭佑 and 小林健 and 朱博 and 井上暁人 and 北口哲也}, title = {教師なしクラスタリングを用いたタンパク質機能予測}, booktitle = {第26回情報論的学習理論ワークショップ (IBIS2023) 要旨集}, year = 2023, } @inproceedings{CTT100920360, author = {Yinghui Yang and Akihito Inoue and Takanobu Yasuda and Bo Zhu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Fabrication of Nanobody-based Ratiometric Bioluminescent Quenchbody for Simple and Rapid Detection}, booktitle = {第75回日本生物工学会大会 要旨集}, year = 2023, } @inproceedings{CTT100911878, author = {Zhu, B. and Qiu, Z. and Mizutani, K. and Kobayashi, K. and Ueda, H. and Kitaguchi, T.}, title = {Rapid development of single fluorescent protein-based immunosensor Flashbody through ultra-high-throughput screening and cell-free protein synthesis}, booktitle = {第75回⽇本⽣物⼯学会⼤会 要旨集}, year = 2023, } @inproceedings{CTT100920359, author = {二宮歩武 and Qian Cheng and 安田貴信 and 朱博 and 北口哲也}, title = {抗原抗体反応が抗体結合タンパク質によって阻害されることを利用した免疫センサーの開発}, booktitle = {第75回日本生物工学会大会 要旨集}, year = 2023, } @inproceedings{CTT100915127, author = {岡田航輝 and 間部悟司 and 加藤晃代 and 朱博 and 北口哲也 and 中野秀雄}, title = {出芽酵母における翻訳促進ペプチドタグに関する研究}, booktitle = {日本農芸化学会中部・関西支部合同大会 要旨集}, year = 2023, } @inproceedings{CTT100920314, author = {北口哲也}, title = {光るタンパク質と抗体が拓く細胞イメージングの世界}, booktitle = {第75回日本生物工学会大会 要旨集}, year = 2023, } @inproceedings{CTT100908477, author = {安田貴信 and 朱博 and 上田宏 and 北口哲也}, title = {抗体結合タンパク質を利用した全長抗体の生物発光センサー化}, booktitle = {化学工学会第54回秋季大会要旨集}, year = 2023, } @inproceedings{CTT100920332, author = {Takeo Matsumoto and Junfeng Wang and Eijiro Maeda and Yuki Tsujimura and Hideo Yokota and Tetsuya Kitaguchi}, title = {Generation of transgenic mice expressing FRET-based tension sensor: masurement with conventional CLSM}, booktitle = {28th Congress of the European Society of Biomechanics}, year = 2023, } @inproceedings{CTT100920313, author = {北口哲也}, title = {機械仕掛けのタンパク質 ~シンガポールでの出会いから始まった万能センサー~}, booktitle = {日本生物工学会 東日本支部生物工学フォーラム 要旨集}, year = 2023, } @inproceedings{CTT100920312, author = {北口哲也}, title = {抗体とタンパク質“機械”}, booktitle = {上田先生を偲ぶ会}, year = 2023, } @inproceedings{CTT100920323, author = {Hiroshi Ueda and Bo Zhu and Jiulong Su and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake.}, title = {The Patrol Yeast: a new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning}, booktitle = {33rd Anniversary World Congress on Biosensors}, year = 2023, } @inproceedings{CTT100920328, author = {Akihito Inoue and Takanobu Yasuda and Tetsuya Kitaguchi and Akikazu Murakami and Hiroshi Ueda.}, title = {Selection and Trp-mutation evolution of a nanobody-based fluorescent immunosensor "nano Q-body" by yeast surface display}, booktitle = {33rd Anniversary World Congress on Biosensors}, year = 2023, } @inproceedings{CTT100920330, author = {Kana Sasamoto and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Development of “Coiled Q-probe” that can effectively convert antibodies into fluorescent immunosensors}, booktitle = {33rd Anniversary World Congress on Biosensors}, year = 2023, } @inproceedings{CTT100899581, author = {大室有紀 and 北口哲也 and 上田宏 and 木村宏}, title = {YFP断片とintrabodyを利用した生細胞内におけるエピジェネティクス変化の観察法構築}, booktitle = {第16回日本エピジェネティクス研究会年会 要旨集}, year = 2023, } @inproceedings{CTT100899566, author = {松本健郎 and 王軍鋒 and 前田英次郎 and 辻村有紀 and 横田秀夫 and 北口哲也}, title = {共焦点顕微鏡で観察が可能なFRET型張力センサを発現するマウスの開発と評価}, booktitle = {第62回日本生体医工学会大会 要旨集}, year = 2023, } @inproceedings{CTT100920317, author = {Tetsuya Kitaguchi}, title = {Fluorescent sensors paving the future of life sciences}, booktitle = {The 2023 RIES – CEFMSJoint International Symposium}, year = 2023, } @inproceedings{CTT100899585, author = {Yuri Osuga and Mai Takizawa and Rika Ishida and Marie Mita and Kazuki Harada and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {Intracellular cGMP dynamics during incretin secretion revealed by red fluorescent protein-based cGMP sensor}, booktitle = {第100回日本生理学会大会要旨集}, year = 2023, } @inproceedings{CTT100899584, author = {Kazuki Harada and Maoko Takashima and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {Temporal shift and involvement of actin in the docking dynamics of biphasic exocytosis of glucagon-like peptide-1.}, booktitle = {第100回日本生理学会大会要旨集}, year = 2023, } @inproceedings{CTT100899567, author = {Tetsuya Kitaguchi}, title = {Molecular evolution paves the way for development of fluorescent protein-based sensors.}, booktitle = {第100回日本生理学会大会要旨集}, year = 2023, } @inproceedings{CTT100887891, author = {井上暁人 and 安田貴信 and 朱博 and 北口哲也 and 村上明一 and 上田宏}, title = {酵母細胞表層提示系を用いたナノ抗体由来”nano Q-body”のTrp変異進化}, booktitle = {化学工学会第88年会要旨集}, year = 2023, } @inproceedings{CTT100887855, author = {佐藤 里杏人 and 安田 貴信 and 朱 博 and 北口 哲也 and 加藤 直洋 and 上田 宏}, title = {3分割ルシフェラーゼを用いた免疫測定法における相互作用の測定と数理モデルの作製}, booktitle = {化学工学会第88年会要旨集}, year = 2023, } @inproceedings{CTT100898138, author = {福嶋 俊明 and 柿原 慧遵 and 浅水 謙吾 and 森次 圭 and 北口 哲也 and 駒田 雅之}, title = {クッシング病を引き起こすUSP8の過剰活性化機構}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100899579, author = {Keisuke Yamashita and Takashi Tsuboi and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Development of a GFP-based biosensor for visualizing intracellular IP3 dynamics}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100899580, author = {大須賀佑里 and 滝澤舞 and 石田りか and 三田真理恵 and 原田一貴 and 北口哲也 and 坪井貴司}, title = {赤色cGMPセンサーを用いた消化管ホルモン分泌におけるcGMPの役割の解明}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100899582, author = {堀越美菜 and 角沙樹 and 北口哲也 and 原田一貴 and 松本光晴 and 坪井貴司}, title = {運動時の肝細胞における乳酸動態の可視化解析}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100899583, author = {Cong Q. Vu and Taketoshi Kiya and Toshinori Fujie and Tetsuya Kitaguchi and Satoshi Arai}, title = {A green color fluorescence lifetime-based ATP biosensor}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100899578, author = {日浅 綜平 and 藤森 武流 and Saki Aiki and 上田 宏 and Takashi Tsuboi and 北口 哲也}, title = {幅広い濃度範囲の検出を可能とする複数の緑色蛍光cAMPセンサーの開発}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100899564, author = {北口 哲也}, title = {分子進化と半合理デザインを駆使した遺伝子コード型蛍光センサーの創出}, booktitle = {第96回日本薬理学会年会要旨集}, year = 2022, } @inproceedings{CTT100899577, author = {笹本佳那 and 安田貴信 and 北口哲也 and 上田宏}, title = {逆並行結合抑制型ペプチドペアによる抗体を蛍光免疫センサに変換するプローブタンパク質Coiled Q-probeの蛍光応答向上}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100887853, author = {塘 知子 and 朱 博 and 北口 哲也 and 上田 宏}, title = {蛍光免疫センサーQuenchbodyのシグナル増幅と高速スクリーニング法の探索}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100899576, author = {井上暁人 and 安田貴信 and 北口哲也 and 村上明一 and 上田宏}, title = {酵母提示系によるナノ抗体由来の蛍光免疫センサnano Q-bodyの分子進化法の開発}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100899571, author = {Hiroshi Ueda and Bo Zhu and Jiulong Su and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake.}, title = {Development of “patrol yeasts” for the detection of multiple toxic substances in foods}, booktitle = {The 15th Asian Congress on Biotechnology}, year = 2022, } @inproceedings{CTT100899575, author = {伊藤良浩 and 佐々木隆一 and 朝里さやか and 北口哲也 and 上田 宏}, title = {微小ドロップレット培養とバイオセンサーを用いたタンパク質高生産株スクリーニング法の開発}, booktitle = {第74回日本生物工学会大会要旨集}, year = 2022, } @inproceedings{CTT100899561, author = {上田宏 and 蘇九龍 and 朱博 and 井上暁人 and 大山浩之 and 森田いずみ and 董金華 and 小西良子 and 北口哲也 and 小林典裕 and 三宅司郎}, title = {各種食中毒から生活者を守る「パトロール酵母」の開発}, booktitle = {第74回日本生物工学会大会要旨集}, year = 2022, } @inproceedings{CTT100899573, author = {倉田晴生 and 安田貴信 and 北口哲也 and 上田宏}, title = {発光タグを付加したペプチドを用いた免疫センサーの構築}, booktitle = {化学工学会第53 回秋季大会要旨集}, year = 2022, } @inproceedings{CTT100899574, author = {Cong Quang Vu and Taketoshi Kiya and Toshinori Fujie and Tetsuya Kitaguchi and Satoshi Arai.}, title = {A green color fluorescence lifetime-based biosensor for quantitative imaging of intracellular ATP in multicellular system}, booktitle = {第60回日本生物物理学会要旨集}, year = 2022, } @inproceedings{CTT100920373, author = {上田 宏 and DAI YANCEN and 佐藤 優子 and 朱 博 and 北口 哲也 and 木村 宏 and Farid J. Ghadessy}, title = {生細胞内タンパク質の動態観察とそれによる細胞分別が可能な蛍光抗体プローブIntra Q-bodyの構築}, booktitle = {第16回バイオ関連化学シンポジウム 要旨集}, year = 2022, } @inproceedings{CTT100898141, author = {Keijun Kakihara and Kei Moritsugu and Tetsuya Kitaguchi and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {Autoinhibition of USP8 by WW-like domain and the dysregulation in Cushing’s disease}, booktitle = {EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”}, year = 2022, } @inproceedings{CTT100887890, author = {井上暁人 and 鈴木大凱 and YANG Yinghui and 安田貴信 and 朱博 and 北口哲也 and 上田宏}, title = {コルチゾール認識ナノ抗体の蛍光免疫センサー化}, booktitle = {第16回バイオ関連化学シンポジウム要旨集}, year = 2022, } @inproceedings{CTT100887859, author = {朱博 and 野坂 宜之 and 董 金華 and 北口 哲也 and 小池 竜 司 and 若林 健二 and 上田 宏}, title = {Converting antibodies to rapid response SARS-CoV-2 homogeneous immunosensors via Quenchbody technology and crowding agent}, booktitle = {化学工学会第53 回秋季大会要旨集}, year = 2022, } @inproceedings{CTT100900707, author = {安田貴信 and 笹本佳那 and 北口哲也 and 上田宏}, title = {逆平行結合抑制ペプチドペアを用いたクエンチ抗体の構築と評価}, booktitle = {第16回バイオ関連化学シンポジウム要旨集}, year = 2022, } @inproceedings{CTT100877602, author = {Bo Zhu and Haimei Li and Yancen Dai and Akihito Inoue and Yinghui Yang and Kaori Kobayashi and Tetsuya Kitaguchi and Jinhua Dong and Hiroshi Ueda}, title = {Rapid construction of homogeneous immunosensors for SARS-CoV-2 nucleocapsid and spike proteins using Quenchbody and Quenchprobe technology}, booktitle = {Bioanalytical Sensors Gordon Research Conference}, year = 2022, } @inproceedings{CTT100899572, author = {王軍鋒 and 辻村有紀 and 北口哲也 and 前田英次郎 and 横田秀夫 and 松本健郎}, title = {FRET型張力センサ発現マウスの血管と腱の引張に伴うFRET変化}, booktitle = {日本機械学会 第34回バイオエンジニアリング講演会要旨集}, year = 2022, } @inproceedings{CTT100920352, author = {Cheng Qian and Bo Zhu and Haoxuan Tang and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Development of a thermostable beta-glucuronidase enzyme switch by introducing mutations that weaken interactions between diagonal subunits}, booktitle = {2022年度生物工学若手研究者の集い 要旨集}, year = 2022, } @inproceedings{CTT100920349, author = {Yinghui Yang and Akihito Inoue and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Fabrication of BRET Q-body Using Various Antibody Fragments}, booktitle = {第10回日本生物工学会東日本支部コロキウム 要旨集}, year = 2022, } @inproceedings{CTT100875235, author = {Yancen Dai and Bo Zhu and Yuko Sato and Hiroshi Kimura and Farid J. Ghadessy and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Development of an immunofluorescence probe Q-body for the direct visualization of tumor marker p53 in fixed and living cells.}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875234, author = {Yanmin Chen and Yancen Dai and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Development of a multicolor Q-body construction method using Escherichia coli.}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875232, author = {椿凜果 and 安田貴信 and 朱博 and 北口哲也 and 上田宏}, title = {蛍光免疫センサーCoiled Quenchbodyのがん光線力学療法への応用}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875230, author = {小林香央里 and 朱博 and 北口哲也 and 上田宏}, title = {蛍光免疫プローブQuenchprobeのダブルラベル化の検討}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875229, author = {Saki Tsuno and Marie Mita and Mina Horikoshi and Tetsuya Kitaguchi and Kazuki Harada Mitsuharu Matsumoto and Takashi Tsuboi.}, title = {In vivo imaging analysis of metabolic functions in the liver.}, booktitle = {第99回日本生理学会大会要旨集}, year = 2022, } @inproceedings{CTT100875228, author = {Mina Horikoshi and Saki Tsuno and Marie Mita and Tetsuya Kitaguchi and Kazuki Harada and Takashi Tsuboi.}, title = {Live-cell imaging analysis of glucose metabolism in hepatocytes.}, booktitle = {第99回日本生理学会大会要旨集}, year = 2022, } @inproceedings{CTT100875227, author = {Marie Mita and Izumi Sugawara and Kazuki Harada and Motoki Ito and Mai Takizawa and Kentaro Ishida and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Visualization of intracellular glucose metabolism dynamics by red fluorescent protein-based glucose indicators.}, booktitle = {第99回日本生理学会大会要旨集}, year = 2022, } @inproceedings{CTT100875226, author = {Kazuki Harada and Maoko Takahsima and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Involvement of intracellular second messengers and cytoskeleton in the exocytosis of intestinal hormone.}, booktitle = {第99回日本生理学会大会要旨集}, year = 2022, } @inproceedings{CTT100875221, author = {本城麻衣 and 相原寛史 and Yanyan Hou and 上田宏 and 伊藤寿朗 and 北口哲也}, title = {抗体を分子認識ドメインとする蛍光タンパク質プローブを用いたジベレリンの定量}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875219, author = {Sohei Hiasa and Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi.}, title = {Development of green fluorescent protein-based indicators visualizing wide-range of cAMP dynamics for live-cell imaging.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875145, author = {Junfeng Wang and Yuki Tsujimura and Tetsuya Kitaguchi and Eijiro Maeda and Hideo Yokota and Takeo Matsumoto.}, title = {Generation and evaluation of transgenic mice expressing tension sensor based on FRET.}, booktitle = {The 11th Asian-Pacific Conference on Biomechanics}, year = 2021, } @inproceedings{CTT100875217, author = {Ippei Tsujimura and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Development of an antibody-based red fluorescent probe and its characterization.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875218, author = {Kazuki Harada and Maoko Takahsima and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Role of intracellular Ca2+ and cAMP in glucagon-like peptide-1 exocytosis from enteroendocrine L cells.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875222, author = {三田真理恵 and 菅原和 and 原田一貴 and 伊藤幹 and 滝澤舞 and 石田賢太郎 and 上田宏 and 北口哲也 and 坪井貴司}, title = {赤色蛍光タンパク質型グルコースセンサーの開発と糖代謝のライブセルイメージング}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875225, author = {柿原慧遵 and 浅水謙吾 and 森次圭 and 北口哲也 and 遠藤彬則 and 木寺詔記 and 池口満徳 and 駒田雅之 and 福嶋俊明}, title = {脱ユビキチン化酵素USP8の自己阻害機構とクッシング病関連変異によるその解除}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875223, author = {安田貴信 and 上野慶行 and 栃尾尚哉 and 八木宏昌 and 北口哲也 and 木川隆則 and 上田宏}, title = {NMRによる新規免疫センサーHibodyの抗原結合に伴う発光活性増大機構の解明}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875220, author = {Keisuke Yamashita and Ippei Tsujimura and Takashi Tsuboi and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Generation of a genetically-encoded IP3 biosensor based on a green fluorescent protein.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875215, author = {笹本佳那 and 安田貴信 and 北口哲也 and 上田宏}, title = {蛍光免疫センサープローブCoiled Q-probeを用いた各種低分子の検出と,FRET型プローブへの展開}, booktitle = {第94回日本生化学会大会要旨集}, year = 2021, } @inproceedings{CTT100875214, author = {安田貴信 and 井上暁人 and 北口哲也 and 上田宏}, title = {レシオ計測が可能な蛍光免疫センサーFRET Coiled Q-bodyにおけるDonor-Acceptor間距離の検討}, booktitle = {第94回日本生化学会大会要旨集}, year = 2021, } @inproceedings{CTT100875216, author = {飯島快斗 and 上野慶行 and 北口哲也 and 上田宏}, title = {発光タグ融合抗体結合タンパク質を用いた新規抗原検出系の構築}, booktitle = {第94回日本生化学会大会要旨集}, year = 2021, } @inproceedings{CTT100875212, author = {井上暁人 and 安田貴信 and 北口哲也 and 村上 明一 and 上田宏}, title = {酵母提示系を用いたナノ抗体由来の蛍光免疫センサ“mini Q-body”選択法の開発}, booktitle = {第 73回日本生物工学会大会要旨集}, year = 2021, } @inproceedings{CTT100875213, author = {Yancen Dai and Atsushi Izutani and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Intracellular detection of tumor suppressor protein p53 by Q-body technology}, booktitle = {第 73回日本生物工学会大会要旨集}, year = 2021, } @inproceedings{CTT100875159, author = {朱博 and 董金華 and 寧雪じょう and 井上暁人 and 北口哲也 and 上田宏}, title = {Quenchbodyを用いた1分間SARS-CoV-2及び変異株の検出法}, booktitle = {化学工学会第52回秋季大会要旨集}, year = 2021, } @inproceedings{CTT100875157, author = {パクジュンテ and 有坂亮汰 and 柴田貴広 and 内田浩二 and 董金華 and 北口哲也 and 上田宏}, title = {ゲノム編集法によるオープンサンドイッチ免疫測定用抗体の産生}, booktitle = {化学工学会第52回秋季大会要旨集}, year = 2021, } @inproceedings{CTT100875155, author = {井上暁人 and 安田貴信 and 北口哲也 and 村上 明一 and 上田宏}, title = {酵母細胞表層提示系を用いた抗ヒト血清アルブミン (HSA)ナノ抗体由来“mini Q-body”の選択}, booktitle = {化学工学会第52回秋季大会要旨集}, year = 2021, } @inproceedings{CTT100875150, author = {王軍鋒 and 辻村 有紀 and 北口哲也 and 前田 英次郎 and 横田 秀夫 and 松本健郎}, title = {FRET型張力センサを発現するトランスジェニックマウスの作製と評価}, booktitle = {}, year = 2021, } @inproceedings{CTT100875144, author = {Akihito Inoue and Yuki Ohmuro and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of mini Q-body using the nanobody to detect chemotherapy agent.}, booktitle = {}, year = 2021, } @inproceedings{CTT100875142, author = {Akihito Inoue and Yuki Ohmuro and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of mini Q-body using the nanobody to detect chemotherapy agent.}, booktitle = {}, year = 2021, } @inproceedings{CTT100875140, author = {Hiroshi Ueda and Jinhua Dong and Takanobu Yasuda and Masaki Takahashi and Kana Sasamoto and Hiroyuki Oyama and Izumi Morita and Hee-Jin Jeong and Tetsuya Kitaguchi and Norihiro Kobayashi.}, title = {PM Q-probe: a fluorescent binding protein that converts many antibodies to a fluorescent biosensor.}, booktitle = {}, year = 2021, } @inproceedings{CTT100854639, author = {新井敏 and サルケア・サティア and 北口哲也}, title = {単色蛍光タンパク質型FLIMセンサーを用いたATPの時空間定量イメージング}, booktitle = {第21回日本蛋白質科学会年会要旨集}, year = 2021, } @inproceedings{CTT100875130, author = {上田宏 and 有坂亮汰 and 朴俊泰 and 董金華 and 柴田貴広 and 大室有紀 and 北口哲也 and 内田浩二}, title = {ゲノム編集法による酸化脂質類の非競合的免疫測定系の構築}, booktitle = {第74回日本酸化ストレス学会・第21回日本NO学会 合同学術集会要旨集}, year = 2021, } @inproceedings{CTT100875135, author = {北口哲也}, title = {蛍光タンパク質センサーの革新を目指すマルチカラー化と分子認識能の多様化}, booktitle = {3大学医工連携オンラインセミナー・Web要旨集}, year = 2021, } @inproceedings{CTT100854634, author = {Xuerao Ning and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of fluorescent biosensor Q-body for detecting recombinant proteins produced in bioprocess}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854632, author = {Junqian Wang and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Development of a novel immunosensor system based on antigen-dependent assembly of fluorescent proteins.}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854633, author = {Yancen Dai and Atsushi Izutani and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Instant detection of tumor suppressor protein p53 by Q-body technology.}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854631, author = {笹本佳那 and 安田貴信 and 北口哲也 and 上田宏}, title = {迅速簡便に高性能な蛍光免疫センサーを構築可能なCoiled Q-probeの創出}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854637, author = {Marie Mita and Mai Takizawa and Rei Nagata and Kazuki Harada and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Sucralose activates intracellular Ca2+ and cAMP signaling in enteroendocrine L cells.}, booktitle = {第98回日本生理学会大会要旨集}, year = 2021, } @inproceedings{CTT100854636, author = {Kazuki Harada and Takumi Nakamura and Taichi Kamiya and Mai Takizawa and Kazuo Nakajima and Tetsuya Kitaguchi and Kunihiro Ohta and Tadafumi Kato and Takashi Tsuboi.}, title = {Mechanism of L-glutamine-induced glucagon-like peptide-1 secretion via taste receptor and cAMP signaling.}, booktitle = {第98回日本生理学会大会要旨集}, year = 2021, } @inproceedings{CTT100854635, author = {Zhu Bo and Dong Jinhua and Xuerao Ning and Akihito Inoue and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Development of quenchbody-based 1-minute SARS-CoV-2 detection assay.}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854629, author = {Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi.}, title = {Development of turn-on type green fluorescent cAMP biosensors applicable to wide range of cAMP dynamics.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854627, author = {Hiroshi Aihara and Yanyan Hou and Hiroshi Ueda and Toshiro Ito and Tetsuya Kitaguchi.}, title = {Development of a plant hormone probe employing antibody as molecular recognition domain for visualizing intracellular dynamics.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854630, author = {Jiulong Su and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake and Hiroshi Ueda.}, title = {Development of patrol yeasts for the detection of toxic substances in foods.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854628, author = {Ippei Tsujimura and Hiroshi Aihara and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Development of a red fluorescent probe inducing its intensity change by antigen binding.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854520, author = {井上暁人 and 安田貴信 and 北口哲也 and 上田宏}, title = {蛍光免疫センサーQ-bodyを提示した酵母細胞の構築と抗原検出}, booktitle = {化学工学会第51回秋季大会要旨集}, year = 2020, } @inproceedings{CTT100854518, author = {上田宏 and 董金華 and 三宅千絢 and 安田貴信 and 髙橋昌樹 and 大山浩之 and 森田いずみ and 北口哲也 and 小林典裕}, title = {抗体を蛍光免疫センサーQ-body 化可能なタンパク質PM Q-probe による各種バイオマーカーの測定}, booktitle = {化学工学会第51回秋季大会要旨集}, year = 2020, } @inproceedings{CTT100854516, author = {Jiulong Su and Yasuyuki Nakamura and Tetsuya Kitaguchi and Jun Ishii and Akihito Kondo and Norihiro Kobayashi and Shiro Miyake and Hiroshi Ueda.}, title = {Development of patrol yeasts for the detection of toxic substances in foods.}, booktitle = {第93回日本生化学会大会要旨集}, year = 2020, } @inproceedings{CTT100854513, author = {Takanobu Yasuda and Akihito Inoue and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Creation and evaluation of immunosensors that enable ratiometric assay by rapid dual-color labeling of antibody fragments.}, booktitle = {第20回日本蛋白質科学会年会要旨集}, year = 2020, } @inproceedings{CTT100854510, author = {Yoshiyuki Ueno and Naoya Tochio and Junqian Wang and Tetsuya Kitaguchi and Takanori Kigawa and Hiroshi Ueda.}, title = {Mechanistic analysis of novel immunosensor Hibody to clarify the antigen-dependent protrusion of tag sequence attached to the antibody N-terminus.}, booktitle = {第20回日本蛋白質科学会年会要旨集}, year = 2020, } @inproceedings{CTT100837740, author = {有坂亮汰 and 北口哲也 and 上田宏}, title = {ハイブリドーマ細胞のゲノム編集によるオープンサンドイッチ免疫測定用人工抗体の生産}, booktitle = {化学工学会第85年会要旨集}, year = 2020, } @inproceedings{CTT100837735, author = {千原貴美 and 三田真理恵 and 菅原和 and 相木彩希 and 早坂優希 and 原田一貴 and 上田宏 and 北口哲也 and 坪井貴司}, title = {蛍光タンパク質を用いた緑色蛍光輝度変化型乳酸センサーの開発}, booktitle = {第42回日本分子生物学会年会要旨集}, year = 2019, } @inproceedings{CTT100837737, author = {高橋昌樹 and 董金華 and 北口哲也 and 上田宏}, title = {抗体結合タンパク質Mからなる蛍光バイオセンサープローブ"Q-probe"の熱安定化と各種抗原検出への応用}, booktitle = {第42回日本分子生物学会年会要旨集}, year = 2019, } @inproceedings{CTT100837739, author = {Kazuki Harada and Takumi Nakamura and Taichi Kamiya and Mai Takizawa and Kazuo Nakajima and Tetsuya Kitaguchi and Kunihiro Ohta and Tadafumi Kato and Takashi Tsuboi.}, title = {Mechanism of L-glutamine-induced glucagon-like peptide-1 secretion from enteroendocrine L cells via amino acid receptors.}, booktitle = {第42回日本分子生物学会年会要旨集}, year = 2019, } @inproceedings{CTT100837734, author = {三田真理恵 and 伊藤幹 and 原田一貴 and 菅原和 and 永田怜 and 芦田翼 and 上田宏 and 坪井貴司 and 北口哲也}, title = {緑色蛍光グルコースセンサーが検出する人工甘味料による膵β細胞のグルコース恒常性攪乱}, booktitle = {第42回日本分子生物学会年会要旨集}, year = 2019, } @inproceedings{CTT100837736, author = {相原寛史 and Yanyan Hou and 上田宏 and 伊藤寿朗 and 北口哲也}, title = {生細胞イメージングを目指した遺伝子コード型ジベレリンプローブの開発}, booktitle = {第42回日本分子生物学会年会要旨集}, year = 2019, } @inproceedings{CTT100837725, author = {Cyrus Beh and Theresa Seah and Jiulong Su and Yuki Ohmuro-Matsuyama and Tetsuya Kitaguchi and Hiroshi Ueda and Shawn Hoon.}, title = {Facile method for creating arrays of lipid-capped elastomer microwells for bioinspired protocellular sensors.}, booktitle = {}, year = 2019, } @inproceedings{CTT100837724, author = {Kaoru Uesugi and Yuki Mori and Johannes Nicolaus Wibisana and Tetsuya Kitaguchi and Osamu Tabata and Keisuke Morishima.}, title = {Design of microstructure for developing fret function induced cell based force sensor.}, booktitle = {}, year = 2019, } @inproceedings{CTT100837730, author = {上杉薫 and ウィビサナ・ジョハネス ニコラウス and 北口哲也 and 田畑修 and 森島圭祐}, title = {細胞利用型力センサの開発を目的とした細胞へのFRET機能遺伝子導入}, booktitle = {第37回日本ロボット学会学術講演会要旨集}, year = 2019, } @inproceedings{CTT100837723, author = {Jiulong Su and Cyrus Beh and Tetsuya Kitaguchi and Yuki Ohmuro and Theresa Seah and Shawn Hoon and Hiroshi Ueda.}, title = {Creation of a novel sensor enzyme and its integration into protocell for digital detection of various anti-epitope tag antibodies.}, booktitle = {}, year = 2019, } @inproceedings{CTT100837731, author = {大室有紀 and 北口哲也 and 木村宏 and 上田宏}, title = {YFP断片融合抗体プローブを用いたヒストン翻訳後修飾検出系の構築}, booktitle = {第 71回日本生物工学会大会要旨集}, year = 2019, } @inproceedings{CTT100837722, author = {上田宏 and 安田貴信 and 上野慶行 and 井上暁人 and 髙橋昌樹 and 大室有紀 and 北口哲也 and 董金華}, title = {Beyond Q-body: 色素修飾が不要な新規免疫測定素子の構築}, booktitle = {第 71回日本生物工学会大会要旨集}, year = 2019, } @inproceedings{CTT100837727, author = {安田貴信 and 北口哲也 and 上田宏}, title = {コイルドコイル形成ペプチドを利用した蛍光ラベル化法による抗体断片の迅速FRETバイオセンサー化}, booktitle = {第19回日本蛋白質科学会年会要旨集}, year = 2019, } @inproceedings{CTT100837726, author = {上野慶行 and 安田貴信 and 大室有紀 and 北口哲也 and 上田宏}, title = {N末にNanoluc由来タグを持つ抗体断片は抗原依存的にNanolucの発光活性を増大させる}, booktitle = {第19回日本蛋白質科学会年会要旨集}, year = 2019, } @inproceedings{CTT100837728, author = {大室有紀 and 北口哲也 and 木村宏 and 上田宏}, title = {分割YFP融合Intrabodyを用いた生細胞内ヒストンアセチル化検出プローブの構築}, booktitle = {第19回日本蛋白質科学会年会要旨集}, year = 2019, } @inproceedings{CTT100837729, author = {井上暁人 and 大室有紀 and 北口哲也 and 上田宏}, title = {ナノ抗体を用いた抗がん剤センサーmini Q-body の構築}, booktitle = {第19回日本蛋白質科学会年会要旨集}, year = 2019, } @inproceedings{CTT100771381, author = {上田宏 and 大室有紀 and 北口哲也}, title = {均相系測定を可能にする抗原応答性標識抗体の創製}, booktitle = {}, year = 2018, } @inproceedings{CTT100759298, author = {上田宏 and 三宅千絢 and 塚原知也 and 高橋昌樹 and 児島智樹 and 鄭熙陳 and 董金華 and 北口哲也 and 大橋広之}, title = {蛍光免疫センサーQ-body迅速構築のための新しい戦略}, booktitle = {化学工学会第49回秋季大会要旨集}, year = 2017, } @misc{CTT100920301, author = {Yinghui Yang and Akihito Inoue and Takanobu Yasuda and Hiroshi Ueda and Bo Zhu and Tetsuya Kitaguchi}, title = {BRET nano Q-body: a nanobody-based ratiometric bioluminescent immunosensor for point-of-care testing}, year = 2024, } @misc{CTT100920303, author = {北口哲也}, title = {抗体が繋いでくれたご縁}, year = 2024, } @misc{CTT100915123, author = {朱博 and 安田貴信 and 北口哲也}, title = {切らずに開く酵素スイッチ}, year = 2024, } @misc{CTT100908474, author = {安田貴信 and 北口哲也}, title = {互いに引き合う螺旋状ペプチド ~二量体形成から細胞療法まで~}, year = 2024, } @misc{CTT100920302, author = {三田真理恵 and 北口哲也}, title = {生体分子を「みえる化」する技術 -単色蛍光タンパク質センサーの革新}, year = 2024, } @misc{CTT100920300, author = {Bo Zhu and Yukihiko Yamasaki and Takanobu Yasuda and Cheng Qian and Zhirou Qiu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Customizable OpenGUS immunoassay: a homogeneous detection system using split β-glucuronidase and label-free antibody}, year = 2023, } @misc{CTT100920205, author = {Satoshi Arai and Hideki Itoh and Cong Quang Vu and Mizuho Nakayama and Masanobu Oshima and Atsuya Morita and Kazuko Okamoto and Satoru Okuda and Aki Teranishi and Madori Osawa and Yoshiteru Tamura and Shigeaki Nonoyama and Megumi Takuma and Toshinori Fujie and Satya Ranjan Sarker and Thankiah Sudhaharan and Taketoshi Kiya and E. Birgitte Lane and Tetsuya Kitaguchi}, title = {qMaLioffG: A single green fluorescent protein FLIM indicator enabling quantitative imaging of endogenous ATP}, year = 2023, } @misc{CTT100908472, author = {安田 貴信 and 北口哲也}, title = {互いに引き合う螺旋状ペプチド : 二量体形成から細胞療法まで}, year = 2023, } @misc{CTT100908473, author = {安田 貴信 and 大森 健太 and 上田宏 and 北口哲也}, title = {トラップ&リリースが拓いた免疫センサーの道と抗体薬物複合体の未来}, year = 2023, } @misc{CTT100920204, author = {Junfeng Wang and Eijiro Maeda and Yuki Tsujimura and Takaya Abe and Hiroshi Kiyonari and Tetsuya Kitaguchi and Hideo Yokota and Takeo Matsumoto}, title = {In situ FRET measurement of cellular tension with confocal laser microscopy}, year = 2023, } @misc{CTT100920203, author = {Bo Zhu and Zhe Du and Yancen Dai and Tetsuya Kitaguchi and Sebastian Behrens and Burckhard Seelig}, title = {Nanodroplet-based reagent delivery into water-in-fluorinated-oil droplets}, year = 2023, } @misc{CTT100899554, author = {三田真理恵 and 坪井貴司 and 北口哲也}, title = {生体内のグルコース検出技術の進展と展望}, year = 2023, } @misc{CTT100887850, author = {Abdul Qawee Rani and Bo Zhu and Hiroshi Ueda and Tetsuya Kitaguchi}, title = {Recent progress in homogeneous immunosensors based on fluorescence or bioluminescence using antibody engineering}, year = 2023, } @misc{CTT100899553, author = {伊藤良浩 and 佐々木隆一 and 朝里さやか and 北口哲也 and 上田 宏}, title = {微小ドロップレット培養とバイオセンサーを用いたタンパク質高生産株スクリーニング法の開発}, year = 2022, } @misc{CTT100899551, author = {Kazuki Harada and Maoko Takashima and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Exocytotic dynamics of glucagon-like peptide-1 from enteroendocrine L cell line is regulated by actin polymerization}, year = 2022, } @misc{CTT100899552, author = {Sohei Hiasa and Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi}, title = {Development of green fluorescent protein-based cAMP indicators with expanded dynamic range and various working ranges}, year = 2022, } @misc{CTT100899550, author = {Bo Zhu and Cheng Qian and Haoxuan Tang and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces}, year = 2022, } @misc{CTT100875119, author = {Ferdinandus and Madoka Suzuki and Yoshie Harada and Satya Ranjan Sarker and Shin’ichi Ishiwata and Tetsuya Kitaguchi and Satoshi Arai.}, title = {Photothermal dye-based subcellular-sized heat spot enabling the modulation of local cellular activities.}, year = 2021, } @misc{CTT100875121, author = {原田一貴 and 北口哲也 and 坪井貴司}, title = {蛍光タンパク質を用いた緑色乳酸センサーとピルビン酸センサーの開発}, year = 2021, } @misc{CTT100875117, author = {Akihito Inoue and Takanobu Yasuda and Bo Zhu and Tetsuya Kitaguchi and Akikazu Murakami and Hiroshi Ueda.}, title = {Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface.}, year = 2021, } @misc{CTT100853023, author = {Keijun Kakihara and Kengo Asamizu and Kei Moritsugu and Masahide Kubo and Tetsuya Kitaguchi and Akinori Endo and Akinori Kidera and Mitsunori Ikeguchi and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain}, year = 2021, } @misc{CTT100837190, author = {北口哲也}, title = {細胞生理機能を操る!人工の受容体から臨床応用まで}, year = 2020, } @misc{CTT100810503, author = {新井敏 and 北口哲也}, title = {細胞内ATPの同時計測を可能にする3色の蛍光センサー}, year = 2019, } @misc{CTT100877445, author = {上田宏 and 北口哲也 and SuJiulong and 三宅 司郎  and 小林 典裕 }, title = {抗体断片を含む人工受容体を細胞膜に提示した酵母とこれを用いた抗原検出法 }, howpublished = {公開特許}, year = 2022, month = {}, note = {特願2020-145870(2020/08/31), 特開2022-040923(2022/03/11)} } @misc{CTT100869590, author = {上田宏 and 北口哲也 and 大室有紀 and 安田貴信 and 井上暁人}, title = {複数の蛍光色素を結合させたペプチドを用いるホモジニアス免疫測定法}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/021899(2020/06/03), WO 2020/246495(2020/10/12)} } @misc{CTT100917020, author = {上田宏 and 北口哲也 and 大室有紀 and 安田貴信 and 井上暁人}, title = {複数の蛍光色素を結合させたペプチドを用いるホモジニアス免疫測定法}, howpublished = {登録特許}, year = 2024, month = {}, note = {特願2021-524873(2020/06/03), WO 2020/246495(2020/10/12), 特許第7461661号(2024/03/27)} } @misc{CTT100869602, author = {上田宏 and 北口哲也 and 大室有紀 and 上野慶行}, title = {レポータータンパク質断片を付加した組換え抗体を用いるホモジニアス免疫測定法}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/020281(2020/05/22), WO 2020/241486(2020/12/03)} } @misc{CTT100869583, author = {上田宏 and SuJiulong and 北口哲也 and 大室有紀}, title = {ホモジニアス免疫測定法に適した酵素変異体}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/002264(2020/01/23), WO 2020/162203(2020/08/13)} } @misc{CTT100831058, author = {上田宏 and SuJiulong and 北口哲也 and 大室有紀 and Shawn Hoon and Cyrus Beh }, title = {バイオセンサー}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2018-207624(2018/11/02), 特開2020-068746(2020/05/07), 特許第7169582号(2022/11/02)} }