@article{CTT100784916, author = {Yoshiaki Masaki and Keishi Yamamoto and Takeshi Inde and Keita Yoshida and Atsuya Maruyama and Tetsuya Nagata and Jun Tanihata and Shin'ichi Takeda and Mitsuo Sekine and Kohji Seio}, title = {Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2018, } @inproceedings{CTT100785114, author = {Y. Masaki and K. Yamamoto and K. Yoshida and Y. Iriyama and H. Nakajima and T. Kanaki and T. Tomori and K. Seio}, title = {Application of 2'-O-carbamoylethyl-type modifications in antisense oligonucleotide}, booktitle = {}, year = 2018, } @inproceedings{CTT100785089, author = {清尾康志 and 正木慶昭 and 山本恵士 and 印出健志 and 入山友輔 and 中島宏之 and 金木達朗 and 黒田雄介 and 古川賢 and 谷端 淳 and 永田哲也 and 武田伸一 and 関根 光雄}, title = {2’-水酸基にカルバモイルエチル型修飾を有する人工核酸を用いたアンチセンス核酸の開発}, booktitle = {}, year = 2017, } @inproceedings{CTT100785091, author = {正木 慶昭 and 宮坂 隆太 and 山本 恵士 and 吉田 圭汰 and 関根 光雄 and 清尾 康志}, title = {糖部修飾オリゴヌクレオチドの変形能解析と二重鎖融解温度の関係}, booktitle = {}, year = 2017, } @inproceedings{CTT100722469, author = {正木 慶昭 and 吉田 圭汰 and 山本 恵士 and 関根 光雄 and 清尾 康志}, title = {糖部化学修飾RNA二重鎖の変形能と二重鎖融解温度の関係}, booktitle = {}, year = 2016, } @inproceedings{CTT100722445, author = {Yoshiaki Masaki and Ryuta Miyasaka and Keishi Yamamoto and Keita Yoshida and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio}, title = {Deformability analysis of chemically modified RNA and its applicability for estimation of RNA duplex stability}, booktitle = {}, year = 2016, } @inproceedings{CTT100724394, author = {山本 恵士 and 正木 慶昭 and 吉田圭汰 and 入山 友輔 and 中嶋 宏之 and 金木 達朗 and 関根 光雄 and 清尾 康志}, title = {2-(N-エチルカルバモイル)エチル構造を有する糖部修飾核酸の合成と性質}, booktitle = {}, year = 2016, } @inproceedings{CTT100724896, author = {Yoshiaki Masaki and Keishi Yamamoto and Takeshi Inde and Tetsuya Nagata and Jun Tanihata and Yusuke Iriyama and Shinishi Takeda and Mitsuo Sekine and KOHJI SEIO}, title = {Enhancement of exon skipping efficiency by using antisense oligonucleotides containing 2-thiothymidine derivatives}, booktitle = {}, year = 2015, } @inproceedings{CTT100723567, author = {Yoshiaki Masaki and Keishi Yamamoto and Takeshi Inde and Tetsuya Nagata and Jun Tanihata and Yusuke Iriyama and Shin'ichi Takeda and Kohji Seio and Mitsuo Sekine}, title = {Enhancement of exon skipping by 2´-O-(N-methylcarbamoyl)ethyl (MCE) and/or nucleobase modified nucleosides incorporation into phosphorothioate oligonucleotides}, booktitle = {}, year = 2015, } @inproceedings{CTT100724858, author = {山本 恵士 and 正木 慶昭 and 石井 陽大 and 印出 健志 and 金森 功吏 and 関根 光雄 and 清尾 康志}, title = {2'-O-メチルカルバモイルエチル修飾2-チオリボチミジンを含むオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2015, } @misc{CTT100846525, author = {清尾康志 and 正木慶昭 and 山本恵士 and 吉田圭汰 and 入山 友輔 and 中嶋 宏之 and 金木 達朗}, title = {人工ヌクレオシド及び人工ヌクレオチド並びに人工オリゴヌクレオチド}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2020-202186(2020/12/04), 特開2021-046433(2021/03/25), 特許第7085739号(2022/06/09)} } @misc{CTT100793185, author = {清尾康志 and 正木慶昭 and 山本恵士 and 吉田圭汰 and 入山 友輔  and 中嶋 宏之 and 金木 達朗 }, title = {人工ヌクレオシド及び人工ヌクレオチド並びに人工オリゴヌクレオチド}, howpublished = {登録特許}, year = 2021, month = {}, note = {特願2018-500218(2017/02/17), 再表2017/142054(2018/12/06), 特許第6853537号(2021/03/16)} }